Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
Eur Rev Med Pharmacol Sci. 2022 Feb;26(4):1215-1223. doi: 10.26355/eurrev_202202_28113.
The aim of this cross-sectional study is to assess community pharmacists' knowledge of the therapeutic aspects of direct oral anticoagulants and warfarin. Another objective was to study the effect of different demographic factors and relevant characteristics on community pharmacists' knowledge of warfarin and direct oral anticoagulants.
The study was conducted prospectively at community pharmacies in the north of Jordan. Community pharmacists were interviewed using a validated questionnaire consisting of three sections. The first section included demographics and other relevant characteristics. The second and third sections included questions about direct oral anticoagulants and warfarin respectively.
A total of 251 participants completed the questionnaire. Two-thirds of participants knew that direct oral anticoagulants are available in Jordan (67.3%). Of the pharmacists who were able to state at least one direct oral anticoagulant, 60.9% knew at least one main indication. More than half of participating pharmacists had insufficient knowledge (57.8%). Almost half of participants (48.6%) were able to state the most important monitoring parameter of warfarin, and 30.7% were able to state one medication that interacts with warfarin. More than half of participating pharmacists had insufficient knowledge (64.9%). In addition, the results showed that degree of pharmacy, years of experience, university from which pharmacy degree was obtained, and year of graduation were significantly associated with warfarin knowledge.
Most participating pharmacists had insufficient knowledge with regards to direct oral anticoagulants and warfarin. Doctor of Pharmacy degree were more knowledgeable with regards to warfarin compared to participants with a bachelor's degree in Pharmacy. Continuing educational programs are required to keep community pharmacists up to date with new developments in the pharmaceutical field.
本横断面研究旨在评估社区药剂师对直接口服抗凝剂和华法林治疗方面的知识。另一个目的是研究不同人口统计学因素和相关特征对华法林和直接口服抗凝剂知识的影响。
该研究在约旦北部的社区药房进行前瞻性研究。社区药剂师使用经过验证的问卷进行访谈,问卷由三个部分组成。第一部分包括人口统计学和其他相关特征。第二和第三部分分别包括关于直接口服抗凝剂和华法林的问题。
共有 251 名参与者完成了问卷。三分之二的参与者知道直接口服抗凝剂在约旦可用(67.3%)。在能够说出至少一种直接口服抗凝剂的药剂师中,60.9%知道至少一种主要适应症。超过一半的参与药剂师知识不足(57.8%)。近一半的参与者(48.6%)能够说出华法林最重要的监测参数,30.7%能够说出一种与华法林相互作用的药物。超过一半的参与药剂师知识不足(64.9%)。此外,结果表明,药房的程度、经验年限、获得药学学位的大学以及毕业年份与华法林知识显著相关。
大多数参与药剂师对华法林和直接口服抗凝剂的知识不足。与具有药学学士学位的参与者相比,药学博士学位的药剂师对华法林的了解更多。需要继续教育培训,使社区药剂师跟上药物领域的新发展。