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骨关节炎患者疼痛对生活质量的影响:来自巴勒斯坦的横断面研究。

The impact of pain on quality of life in patients with osteoarthritis: a cross-sectional study from Palestine.

机构信息

Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.

Department of Orthopedic Surgery, An-Najah National University Hospital, Nablus, 44839, Palestine.

出版信息

BMC Musculoskelet Disord. 2022 Mar 14;23(1):248. doi: 10.1186/s12891-022-05207-x.

Abstract

BACKGROUND

Osteoarthritis is one of the most common musculoskeletal problems. Pain is the most common complaint and the most significant cause of decreased health-related quality of life (HRQOL) among osteoarthritic patients. The objectives of this study were to assess the impact of pain on quality of life among patients with osteoarthritis and to assess the association of sociodemographic and clinical factors with HRQOL.

METHODS

Using a cross-sectional study design, we collected data from osteoarthritis patients in orthopedic outpatient clinics from four hospitals in the Palestine-West bank between November 2020 and March 2021. We used the Brief Pain Inventory (BPI) scale to assess pain and the Quality of Life scale five dimensions (EQ-5D) with the visual analog scale of the European Quality of Life (EQ-VAS) to assess HRQOL.

RESULTS

In our study, 196 patients composed the final sample, with an average of 60.12 ± 13.63 years. The medians for the EQ-5D score and EQ-VAS score were 0.72 (0.508-0.796) and 70 (55-85), respectively. The pain severity score was found to have a significant negative association with both the EQ-5D and EQ-VAS scores with r of - 0.620, p <  0.001, and - 0.554, p <  0.001, respectively. Similar associations were found between pain interference score and both EQ-5D (r = - 0.822, p <  0.001) and EQ-VAS scores (r = - 0.609, p <  0.001). Multiple regression analysis showed that participants with higher educational level (p = 0.028), less diseased joints (p = 0.01), shorter duration of disease (p = 0.04), and lesser pain severity and interference scores (both with p < 0.001) had significantly higher HRQOL scores.

CONCLUSIONS

We found that many variables have a significant negative impact on HRQOL among patients with osteoarthritis. Our finding provides a well-founded database to use by clinicians and healthcare professionals who work with patients with osteoarthritis, as well as educational and academic institutions.

摘要

背景

骨关节炎是最常见的肌肉骨骼问题之一。疼痛是最常见的主诉,也是骨关节炎患者健康相关生活质量(HRQOL)下降的最主要原因。本研究的目的是评估疼痛对骨关节炎患者生活质量的影响,并评估社会人口学和临床因素与 HRQOL 的相关性。

方法

采用横断面研究设计,于 2020 年 11 月至 2021 年 3 月期间从巴勒斯坦西岸四家医院的骨科门诊收集骨关节炎患者的数据。我们使用简短疼痛量表(BPI)评估疼痛,使用欧洲生活质量五维量表(EQ-5D)的视觉模拟量表(EQ-VAS)评估 HRQOL。

结果

在本研究中,196 例患者构成了最终样本,平均年龄为 60.12±13.63 岁。EQ-5D 评分和 EQ-VAS 评分的中位数分别为 0.72(0.508-0.796)和 70(55-85)。疼痛严重程度评分与 EQ-5D 和 EQ-VAS 评分均呈显著负相关,相关系数分别为-0.620(p<0.001)和-0.554(p<0.001)。疼痛干扰评分与 EQ-5D(r=-0.822,p<0.001)和 EQ-VAS 评分(r=-0.609,p<0.001)也存在类似的相关性。多元回归分析显示,文化程度较高(p=0.028)、关节病变较少(p=0.01)、疾病病程较短(p=0.04)以及疼痛严重程度和干扰评分较低的患者(均 p<0.001)具有更高的 HRQOL 评分。

结论

我们发现许多变量对骨关节炎患者的 HRQOL 有显著的负面影响。我们的研究结果为临床医生和与骨关节炎患者合作的医疗保健专业人员以及教育和学术机构提供了一个可靠的数据库。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b523/8922870/9f0a10e44ea9/12891_2022_5207_Fig1_HTML.jpg

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