奥密克戎（B.1.1.529）变体及其谱系的挑战：全球视角。
Challenges of the Omicron (B.1.1.529) Variant and Its Lineages: A Global Perspective.
机构信息
Department of Chemistry, Government College of Engineering, Keonjhar, 758002, Odisha, India.
Department of Microbiology, Prathima Institute of Medical Sciences, Karimnagar, 505417, Telangana, India.
出版信息
Chembiochem. 2022 May 4;23(9):e202200059. doi: 10.1002/cbic.202200059. Epub 2022 Mar 23.
Abstract
The SARS-CoV-2 virus has shown increased ability to mutate over the past two years, especially in the regions of the spike protein and receptor binding sites. Omicron (B.1.1.529) is the fifth variant of concern (VOC) after the emergence of the Alpha, Beta, Gamma, and Delta VOCs of SARS-CoV-2. This new variant has now circulated in 128 countries and according to the Global Initiative on Sharing All Influenza Data (GISAID), these 128 countries have shared 650,657 Omicron genome sequences as of 26 January, 2022. In this article, we highlight the real challenges of Omicron and its different lineages.
摘要
过去两年中，SARS-CoV-2 病毒的突变能力明显增强，尤其是在刺突蛋白和受体结合部位。奥密克戎（B.1.1.529）是继 Alpha、Beta、Gamma 和 Delta 变异株之后出现的第五种关切变异株（VOC）。目前该新变异株已在 128 个国家传播，根据全球共享流感数据倡议组织（GISAID）的数据，截至 2022 年 1 月 26 日，这 128 个国家已共享了 650657 份奥密克戎基因组序列。本文重点介绍了奥密克戎及其不同谱系带来的实际挑战。
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