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中国重庆儿童流感暴发的流行病学和临床特征。

Epidemiological and Clinical Characteristics of Influenza Outbreaks Among Children in Chongqing, China.

机构信息

Department of Epidemiology and Health Statistics, School of Public Health and Management, Chongqing Medical University, Chongqing, China.

Clinical College, Chongqing Medical University, Chongqing, China.

出版信息

Front Public Health. 2022 Apr 15;10:760746. doi: 10.3389/fpubh.2022.760746. eCollection 2022.

Abstract

Influenza is a global serious public health threat. Seasonal influenza among children in Chongqing has been a heavy health burden. To date, few studies have examined the spatial and temporal characteristics of influenza. This research sheds new light on correlating them with influenza outbreaks with data of over 5 years (2014-2018). All cluster outbreaks among preschool and school-age children reported in Chongqing were collected through the Public Health Emergency Management Information System. The demographical, epidemiological, and clinical data of the cases were analyzed. From 2014 to 2018, a total of 111 preschool- and school-based influenza-like illness outbreaks involving 3,549 cases were identified. Several clinical symptoms that were analyzed in this study showed significant contrast between influenza A and B. Spatial autocorrelation analysis over the 5-year data detected Xiushan district being the most likely cluster. The exploration of the spatial distribution and clinical characteristics of influenza cluster of children in Chongqing could help the effective implementation of health policies. Future studies should be conducted to monitor the outbreaks of influenza among children.

摘要

流感是全球严重的公共卫生威胁。重庆儿童季节性流感一直是沉重的健康负担。迄今为止,很少有研究探讨流感的时空特征。本研究利用超过 5 年(2014-2018 年)的数据,对流感爆发与流感时空特征的相关性进行了新的分析。通过公共卫生应急管理信息系统,收集了重庆市报告的所有学前和学龄儿童聚集性暴发的病例。对病例的人口统计学、流行病学和临床数据进行了分析。2014 年至 2018 年,共发现 111 起学前和学龄儿童流感样疾病暴发,涉及 3549 例。本研究分析的一些临床症状表明,A 型和 B 型流感之间存在显著差异。对 5 年数据的空间自相关分析发现,秀山县最有可能出现聚集性流感。探讨重庆市儿童流感聚集的空间分布和临床特征有助于有效实施卫生政策。未来应开展研究,监测儿童流感爆发情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/654b/9051075/eb01518ef3e4/fpubh-10-760746-g0001.jpg

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