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饮食和营养在 SARS-CoV-2 感染中的作用:对氧化应激、炎症状态和病毒产生的影响。

Role of Diet and Nutrients in SARS-CoV-2 Infection: Incidence on Oxidative Stress, Inflammatory Status and Viral Production.

机构信息

Laboratory Biomathématique, Biochimie, Biophysique et Scientométrie, Faculté des Sciences de la Nature et de la Vie, Université de Bejaia, Bejaia 06000, Algeria.

Department of Biochemistry of the Peroxisome, Inflammation and Lipid Metabolism, University of Bourgogne Franche-Comte, 21000 Dijon, France.

出版信息

Nutrients. 2022 May 25;14(11):2194. doi: 10.3390/nu14112194.

Abstract

Coronavirus illness (COVID-19) is an infectious pathology generated by intense severe respiratory syndrome coronavirus 2 (SARS-CoV-2). This infectious disease has emerged in 2019. The COVID-19-associated pandemic has considerably affected the way of life and the economy in the world. It is consequently crucial to find solutions allowing remedying or alleviating the effects of this infectious disease. Natural products have been in perpetual application from immemorial time given that they are attested to be efficient towards several illnesses without major side effects. Various studies have shown that plant extracts or purified molecules have a promising inhibiting impact towards coronavirus. In addition, it is substantial to understand the characteristics, susceptibility and impact of diet on patients infected with COVID-19. In this review, we recapitulate the influence of extracts or pure molecules from medicinal plants on COVID-19. We approach the possibilities of plant treatment/co-treatment and feeding applied to COVID-19. We also show coronavirus susceptibility and complications associated with nutrient deficiencies and then discuss the major food groups efficient on COVID-19 pathogenesis. Then, we covered emerging technologies using plant-based SARS-CoV-2 vaccine. We conclude by giving nutrient and plants curative therapy recommendations which are of potential interest in the COVID-19 infection and could pave the way for pharmacological treatments or co-treatments of COVID-19.

摘要

冠状病毒病(COVID-19)是由强烈的严重呼吸系统综合征冠状病毒 2(SARS-CoV-2)引起的传染病。这种传染病于 2019 年出现。与 COVID-19 相关的大流行极大地影响了世界的生活方式和经济。因此,找到可以缓解或减轻这种传染病影响的解决方案至关重要。天然产品自古以来就一直在使用,因为它们被证明对多种疾病有效,而且没有重大副作用。各种研究表明,植物提取物或纯化分子对冠状病毒具有有前途的抑制作用。此外,了解饮食对 COVID-19 患者的特点、易感性和影响也很重要。在这篇综述中,我们总结了药用植物提取物或纯分子对 COVID-19 的影响。我们探讨了植物治疗/联合治疗和喂养应用于 COVID-19 的可能性。我们还展示了冠状病毒的易感性和与营养缺乏相关的并发症,然后讨论了对 COVID-19 发病机制有效的主要食物组。然后,我们介绍了基于植物的 SARS-CoV-2 疫苗的新兴技术。最后,我们给出了营养和植物治疗建议,这些建议对 COVID-19 感染具有潜在的重要意义,并为 COVID-19 的药物治疗或联合治疗铺平了道路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fe3/9182601/1bcf66630bff/nutrients-14-02194-g001.jpg

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