Department of General Surgery, The First Hospital of Changsha, Changsha 410005, Hunan, China.
Department of Radiology, The First Hospital of Changsha, Changsha 410005, Hunan, China.
Contrast Media Mol Imaging. 2022 May 31;2022:3038308. doi: 10.1155/2022/3038308. eCollection 2022.
This study was carried out to explore the preoperative predictive value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in extramural vascular invasion (EMVI) in patients with rectal cancer. 124 patients with rectal cancer were randomly divided into two groups, with 62 groups in each group. One group used conventional magnetic resonance imaging (MRI) and was recorded as the control group. The other group used DCE-MRI and was recorded as the experimental group. The diagnostic value was evaluated by comparing the MRI quantitative parameters of EMVI positive and EMVI negative patients, as well as the area under the curve (AUC) of the receiver operating characteristic curve (ROC), diagnostic sensitivity, and specificity of the two groups. The results showed that the Ktrans and Ve values of EMVI positive patients in the experimental group and the control group were 1.08 ± 0.97 and 1.03 ± 0.93, and 0.68 ± 0.29 and 0.65 ± 0.31, respectively, which were significantly higher than those in EMVI negative patients ( < 0.05). The AUC of EMVI diagnosis in the experimental group and the control group were 0.732 and 0.534 ( < 0.05), the sensitivity was 0.913 and 0.765 ( < 0.05), and the specificity was 0.798 and 0.756 ( > 0.05), respectively. In conclusion, DCE-MRI has a higher diagnostic value than conventional MRI in predicting EMVI in patients with rectal cancer, which was worthy of further clinical promotion.
本研究旨在探讨动态对比增强磁共振成像(DCE-MRI)在直肠癌患者外突血管侵犯(EMVI)术前预测中的价值。将 124 例直肠癌患者随机分为两组,每组 62 例。一组采用常规磁共振成像(MRI),记录为对照组。另一组采用 DCE-MRI,记录为实验组。通过比较 EMVI 阳性和 EMVI 阴性患者的 MRI 定量参数以及两组患者的曲线下面积(AUC)、受试者工作特征曲线(ROC)的诊断敏感性和特异性,评估诊断价值。结果显示,实验组和对照组 EMVI 阳性患者的 Ktrans 和 Ve 值分别为 1.08±0.97 和 1.03±0.93,0.68±0.29 和 0.65±0.31,均显著高于 EMVI 阴性患者( < 0.05)。实验组和对照组 EMVI 诊断的 AUC 分别为 0.732 和 0.534( < 0.05),灵敏度分别为 0.913 和 0.765( < 0.05),特异性分别为 0.798 和 0.756( > 0.05)。综上所述,DCE-MRI 对预测直肠癌患者 EMVI 的诊断价值高于常规 MRI,值得进一步临床推广。