Agricultural Biotechnology Department, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Biochemistry Department, Faculty of Agriculture, Cairo University, Giza 12613, Egypt.
Mar Drugs. 2022 May 24;20(6):342. doi: 10.3390/md20060342.
Since ancient times, seaweeds have been employed as source of highly bioactive secondary metabolites that could act as key medicinal components. Furthermore, research into the biological activity of certain seaweed compounds has progressed significantly, with an emphasis on their composition and application for human and animal nutrition. Seaweeds have many uses: they are consumed as fodder, and have been used in medicines, cosmetics, energy, fertilizers, and industrial agar and alginate biosynthesis. The beneficial effects of seaweed are mostly due to the presence of minerals, vitamins, phenols, polysaccharides, and sterols, as well as several other bioactive compounds. These compounds seem to have antioxidant, anti-inflammatory, anti-cancer, antimicrobial, and anti-diabetic activities. Recent advances and limitations for seaweed bioactive as a nutraceutical in terms of bioavailability are explored in order to better comprehend their therapeutic development. To further understand the mechanism of action of seaweed chemicals, more research is needed as is an investigation into their potential usage in pharmaceutical companies and other applications, with the ultimate objective of developing sustainable and healthier products. The objective of this review is to collect information about the role of seaweeds on nutritional, pharmacological, industrial, and biochemical applications, as well as their impact on human health.
自古以来,海藻就被用作具有高度生物活性的次生代谢产物的来源,这些产物可以作为关键的药用成分。此外,对某些海藻化合物的生物活性的研究已经取得了显著进展,重点是它们的组成及其在人类和动物营养方面的应用。海藻有许多用途:它们可以作为饲料被食用,也可以用于药品、化妆品、能源、肥料以及工业琼脂和藻酸盐的生物合成。海藻的有益作用主要归因于矿物质、维生素、酚类、多糖和固醇以及其他几种生物活性化合物的存在。这些化合物似乎具有抗氧化、抗炎、抗癌、抗菌和抗糖尿病的活性。本文探讨了海藻生物活性作为一种营养保健品在生物利用度方面的最新进展和局限性,以便更好地理解其治疗开发。为了进一步了解海藻化学物质的作用机制,需要开展更多的研究,并探讨它们在制药公司和其他应用中的潜在用途,最终目标是开发更可持续和更健康的产品。本综述的目的是收集有关海藻在营养、药理学、工业和生化应用方面的作用及其对人类健康影响的信息。