膝关节置换术后急性血源性人工关节感染的清创与植入物保留：一项系统评价
Debridement and implant retention in acute hematogenous periprosthetic joint infection after knee arthroplasty: a systematic review.
作者信息
Balato Giovanni, Ascione Tiziana, de Matteo Vincenzo, Lenzi Marco, Amato Massimiliano, de Giovanni Roberto, Festa Enrico, Mariconda Massimo
机构信息
Department of Public Health, Orthopedic Unit, "Federico II" University, Naples (Italy).
Service of Infectious Diseases, AORN Cardarelli Hospital, Naples (Italy).
出版信息
Orthop Rev (Pavia). 2022 Apr 25;14(2):33670. doi: 10.52965/001c.33670. eCollection 2022.
Abstract
Debridement, antibiotic, and implant retention (DAIR) can be used as a first surgical procedure for acute infections in patients who have well-fixed components. However, its use in hematogenous or late acute infections is still debated. This systematic review of literature aims to clarify the effectiveness of DAIR procedure in the treatment of hematogenous periprosthetic knee infections. DAIR is an effective way to treat acute hematogenous PJIs of the knee and reaches its best efficacy when performed within one week from the onset of symptoms, modular components are exchanged, and a pathogen-oriented antibiotic therapy can be set. It is safe, economic, and effective technique, but has to be performed in a very narrow temporal window.
摘要
清创、抗生素及植入物保留（DAIR）可作为初次手术方法用于假体组件固定良好的患者的急性感染。然而，其在血源性或晚期急性感染中的应用仍存在争议。本系统文献综述旨在阐明DAIR手术治疗血源性人工膝关节感染的有效性。DAIR是治疗膝关节急性血源性假体周围感染的有效方法，在症状出现后一周内进行、更换模块化组件并采用针对性抗生素治疗时效果最佳。它是一种安全、经济且有效的技术，但必须在非常狭窄的时间窗内进行。
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