Department of Statistics, College of Natural and Computational Science, Wolaita Sodo University, Wolaita Sodo P.O. Box 138, Ethiopia.
Department of Statistics, College of Science, Engineering and Technology (CSET), University of South Africa (UNISA), Pretoria 0002, South Africa.
Nutrients. 2022 Jun 28;14(13):2693. doi: 10.3390/nu14132693.
Anaemia is a condition characterised by a decrease in the concentration of haemoglobin (Hb) in the blood. Anaemia suffers under five years children about 47.4% and 67.6% worldwide and developing countries including Ethiopia, respectively. The aim of this study was to assess the prevalence rate and the associated socio-economic, geographic and demographic factors of anaemia status of under five years children in Ethiopia. The data for this study were obtained from the 2011 Ethiopia National Malaria Indicator Survey (EMIS 2011). A sample of 4356 under five years age children was obtained from three regional states of Ethiopia. Based on haemoglobin level, child anaemia status was ordered and takes an ordinal value as no anaemia, mild anaemia, moderate anaemia and severe anaemia, respectively. Ordinal logistic regression model, specifically the proportional odds model was used by considering with and without survey design features. Of the 4356 complete cases, 2190 (50.28%) were male and 1966 (49.72%) were female children under five years old. The children overall mean (SD) age was 2.68 (1.21) years. It was observed that both the mean ages and their variabilities in the regions are approximately equal to the overall mean and variability. It was also observed that in Amhara, Oromiya and SNNP regions 72.28%, 67.99% and 73.63% of the children, respectively had no anaemia; 15.93%, 13.47% and 13.56% of the children, respectively had mild anaemia; 10.99%, 15.61% and 11.33% of the children, respectively had moderate anaemia; and only 0.81%, 2.93% and 1.49% had severe anaemia, respectively. The prevalence of severe child anaemia status was higher in Oromiya region compared to Amhara and SNNP regions, respectively. Our result indicates that age, use of mosquito net, malaria RDT outcome, type of toilet facility, household wealth index, region and median altitude were significantly related to child anaemia status. However, it was observed that some covariates were model dependent, for example household wealth index and type of toilet facility were not significant when considering survey features. Anaemia burden remains high particularly in developing countries. Controlling the burden of anaemia necessitates the formulation of integrated interventions which prioritise the highest risk groups including children under five years. The statistical model used in this paper identified individual, household and cluster level risk factors of child anaemia. The identified risk factors for example not having improved toilet facility in the dwelling where a child lived as well as poorest household wealth index suggest the policymakers should target to focus more on children from poor community. Further, the strong association between malaria infection and anaemia suggests that malaria preventative methods such as vector control methods namely, long-lasting insecticidal nets (LLINs) and indoor residual spraying of households with insecticides and including case diagnostic testing and treatment may be the most effective ways to reduce infections associated with anaemia. Such collective assessment approach may lead to more effective public health strategies and could have important policy implications for health promotion and for the reduction of health disparities.
贫血是一种以血液中血红蛋白(Hb)浓度降低为特征的疾病。全世界五岁以下儿童贫血患病率约为 47.4%,发展中国家,包括埃塞俄比亚,分别为 67.6%。本研究旨在评估埃塞俄比亚五岁以下儿童贫血状况的流行率及其相关的社会经济、地理和人口统计学因素。本研究的数据来自 2011 年埃塞俄比亚国家疟疾指标调查(EMIS 2011)。从埃塞俄比亚三个地区州获得了 4356 名五岁以下儿童的样本。根据血红蛋白水平,儿童贫血状况被排序,并采用有序值,分别为无贫血、轻度贫血、中度贫血和重度贫血。考虑到调查设计特征,使用了有序逻辑回归模型,特别是比例优势模型。在 4356 例完整病例中,2190 例(50.28%)为男性,1966 例(49.72%)为五岁以下儿童。儿童的总体平均(SD)年龄为 2.68(1.21)岁。观察到各地区的平均年龄及其变异性与总体平均年龄和变异性大致相等。还观察到,在阿姆哈拉、奥罗莫和南南合作区域,分别有 72.28%、67.99%和 73.63%的儿童没有贫血;分别有 15.93%、13.47%和 13.56%的儿童患有轻度贫血;分别有 10.99%、15.61%和 11.33%的儿童患有中度贫血;只有 0.81%、2.93%和 1.49%的儿童患有严重贫血。与阿姆哈拉和南南合作地区相比,奥罗莫地区严重儿童贫血状况的患病率更高。我们的结果表明,年龄、使用蚊帐、疟疾快速诊断检测结果、厕所设施类型、家庭财富指数、地区和中值海拔与儿童贫血状况显著相关。然而,观察到一些协变量取决于模型,例如,当考虑到调查特征时,家庭财富指数和厕所设施类型并不显著。贫血负担在发展中国家仍然很高。控制贫血负担需要制定综合干预措施,优先考虑包括五岁以下儿童在内的高风险群体。本文使用的统计模型确定了儿童贫血的个体、家庭和群体风险因素。所确定的风险因素,例如儿童居住的住所没有改善的卫生设施以及最贫穷的家庭财富指数,表明决策者应更加关注来自贫困社区的儿童。此外,疟疾感染与贫血之间的强烈关联表明,疟疾预防方法,如控制蚊虫的方法,即长效驱虫蚊帐(LLINs)和家庭内用杀虫剂进行室内滞留喷洒,以及包括病例诊断检测和治疗,可能是减少与贫血相关感染的最有效方法。这种综合评估方法可能会导致更有效的公共卫生策略,并对健康促进和减少健康差距产生重要政策影响。