新冠疫苗及新型冠状病毒变体的进展
Advances in COVID-19 Vaccines and New Coronavirus Variants.
作者信息
Liu Mengchen, Li Yunqiao
机构信息
Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
出版信息
Front Med (Lausanne). 2022 Jul 8;9:888631. doi: 10.3389/fmed.2022.888631. eCollection 2022.
With the successful development of the Corona Virus Disease 2019 (COVID-19) vaccines and increased vaccination coverage, great progress in global outbreak control has been made in several countries. However, new coronavirus variants emerge and their rapid spread, causing a new wave of economic and social upheaval worldwide. The spread of new coronavirus variants poses a new and enormous challenge to vaccination and pandemic control, so further studies to explore and develop vaccines for the prevention and control virus infection are warranted. In this review, we provide an overview of the most prevalent variants including Omicron, and explore the effectiveness of COVID-19 vaccines against related variants to better understand existing vaccines and to facilitate improved research into new vaccines. In addition, this review discusses existing strategies to increase vaccine efficacy and introduces novel vaccines by the non-injection route.
随着2019冠状病毒病（COVID-19）疫苗的成功研发以及疫苗接种覆盖率的提高，一些国家在全球疫情控制方面取得了巨大进展。然而，新冠病毒变异株不断出现并迅速传播，在全球范围内引发了新一轮的经济和社会动荡。新冠病毒变异株的传播给疫苗接种和疫情防控带来了新的巨大挑战，因此有必要进一步开展研究以探索和研发用于预防和控制病毒感染的疫苗。在本综述中，我们概述了包括奥密克戎在内的最流行变异株，并探讨了COVID-19疫苗对相关变异株的有效性，以便更好地了解现有疫苗，并促进新型疫苗研发的改进。此外，本综述讨论了提高疫苗效力的现有策略，并介绍了非注射途径的新型疫苗。
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