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创伤后三叉神经痛性疼痛:影响手术治疗结果的因素

Post-traumatic Trigeminal Neuropathic Pain: Factors Affecting Surgical Treatment Outcomes.

作者信息

Neal Timothy W, Zuniga John R

机构信息

Division of Oral and Maxillofacial Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, United States.

出版信息

Front Oral Health. 2022 Jul 7;3:904785. doi: 10.3389/froh.2022.904785. eCollection 2022.

Abstract

Post-traumatic trigeminal neuropathic pain (PTTNp) is a painful condition that may result from injury to the sensory division of the trigeminal nerve. Treatment of this condition is challenging and consensus on treatment to resolve neuropathic pain has yet to be standardized. Equally as challenging is the identification of surgical outcome variables to guide surgical treatment of PTTNp. This is partly due to the variability in pain characteristics, severity of nerve injury, location, and duration from injury to surgery. In those with neuropathic pain prior to microsurgical intervention, the incidence of neuropathic pain after microsurgical intervention is 67%. It is unclear why nerve repair surgery is effective in resolving or decreasing neuropathic pain in some patients, whereas it has no effect on pain relief in others. Psychological, medical, and age-related factors have been identified as risk factors for developing chronic post-surgical pain due to post-traumatic neuropathic pain. Two factors: injury to surgery time and preoperative visual analog scale score have recently been identified as variables that influence surgical outcomes in the treatment of PTTNp.

摘要

创伤后三叉神经病理性疼痛(PTTNp)是一种可能由三叉神经感觉支损伤引起的疼痛病症。这种病症的治疗具有挑战性,关于解决神经性疼痛的治疗方法尚未标准化。同样具有挑战性的是确定手术结果变量以指导PTTNp的手术治疗。部分原因在于疼痛特征、神经损伤严重程度、位置以及从损伤到手术的持续时间存在差异。在显微手术干预前患有神经性疼痛的患者中,显微手术干预后神经性疼痛的发生率为67%。目前尚不清楚为什么神经修复手术在一些患者中能有效解决或减轻神经性疼痛,而在其他患者中对缓解疼痛却没有效果。心理、医学和年龄相关因素已被确定为创伤后神经性疼痛导致慢性术后疼痛的风险因素。最近已确定两个因素:损伤至手术时间和术前视觉模拟量表评分是影响PTTNp治疗手术结果的变量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b29d/9301486/05d5e9a4a758/froh-03-904785-g0001.jpg

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