Antimicrobial Resistance of in Bloodstream Infections in Hospitalized Patients in Southern Poland.

The aim of this study was to highlight antimicrobial resistance among isolated from bloodstream infections in hospitals in southern Poland. The present study includes laboratory-confirmed secondary bloodstream infections (LC-BSIs), in the years 2015-2018, in hospitalized adult patients (≥18). Episodes of BSIs were defined according to the strictly described guidelines. Antimicrobial susceptibility testing was performed with the automated system and the disc diffusion method. Extended-spectrum β-lactamases (ESBLs)-producing were detected using the double-disc synergy test. Between 2015 and 2018, 356 episodes of secondary BSIs in 997 patients aged 21-96 years were documented in a prospective study, including 134 (37.6%) ESBL-producing . was the predominant pathogen in internal medicine (37.6%) and surgery units (46.8%); in intensive care units (ICUs), was isolated more frequently (33.3%). were highly resistant to most antimicrobial agents. isolates had a higher level of resistance than , regardless of the unit. The increase in AMR and the widespread distribution of ESBL-producing in Polish hospitals can be related to the lack of or inappropriate antibiotic treatment.