Yeh Nai-Hua, Zhu Yu, Moeller Kevin D
Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130 (USA).
ChemElectroChem. 2019 Aug 16;6(16):4134-4143. doi: 10.1002/celc.201900851. Epub 2019 Jun 26.
In this short review, an electroorganic synthesis approach to the construction of addressable, complex molecular surfaces is described along with the parameters that guided the development of that synthetic approach. The result of the work is a synthetic toolbox that will allow microelectrode arrays to be used for the "real-time" monitoring of small molecule interactions with biological targets.
在这篇简短的综述中,描述了一种用于构建可寻址复杂分子表面的有机电合成方法以及指导该合成方法发展的参数。这项工作的成果是一个合成工具箱,它将使微电极阵列能够用于“实时”监测小分子与生物靶点的相互作用。