Jat Kana Ram, Banothu Kiran Kumar, Lodha Rakesh, Jana Manisha, Kabra Sushil K
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.
Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
Indian J Pediatr. 2022 Dec;89(12):1257-1259. doi: 10.1007/s12098-022-04349-z. Epub 2022 Aug 25.
Allergic bronchopulmonary aspergillosis (ABPA) is an IgE-mediated hypersensitivity reaction predominantly occurring in patients of asthma and cystic fibrosis. The typical radiological findings in ABPA include central bronchiectasis and fleeting opacities. In this retrospective study, the aim was to describe cases of ABPA in children who had a mass-like lesion in the lung. There were 5 cases of ABPA in children, who presented as mass-like lesions that responded very well to treatment for ABPA. All cases, except 1, had asthma as the underlying disease. There was a delay in the diagnosis of ABPA in all 5 cases. There had been unnecessary invasive investigations in some of these cases before the diagnosis of ABPA was made. To conclude, children with ABPA may present with a mass-like lesion in the lung and high index of suspicion is required to diagnose ABPA timely to prevent its consequences.
变应性支气管肺曲霉病(ABPA)是一种主要发生在哮喘和囊性纤维化患者中的IgE介导的超敏反应。ABPA的典型影像学表现包括中心性支气管扩张和短暂性肺实变。在这项回顾性研究中,目的是描述肺部有肿块样病变的儿童ABPA病例。有5例儿童ABPA病例,表现为肿块样病变,对ABPA治疗反应良好。除1例以外,所有病例均以哮喘为基础疾病。所有5例ABPA诊断均有延迟。在这些病例中的一些在ABPA诊断之前进行了不必要的侵入性检查。总之,患有ABPA的儿童可能会出现肺部肿块样病变,需要高度怀疑才能及时诊断ABPA以预防其后果。