对比敏感度评估在糖尿病视网膜病变早期诊断中的应用：一项系统评价
Contrast Sensitivity Assessment in Early Diagnosis of Diabetic Retinopathy: A Systematic Review.
作者信息
Silva-Viguera María-Carmen, García-Romera Marta-C, López-Izquierdo Inmaculada, De-Hita-Cantalejo Concepción, Sánchez-González María Carmen, Bautista-Llamas María-José
机构信息
Department of Physics of Condensed Matter, Optics Area. Vision Research Group (CIVIUS), University of Seville, Seville, Spain.
出版信息
Semin Ophthalmol. 2023 May;38(4):319-332. doi: 10.1080/08820538.2022.2116289. Epub 2022 Sep 1.
INTRODUCTION
The purpose of this systematic review was to study whether contrast sensitivity assessment in people with diabetes could be a reliable test in early detection of diabetic retinopathy. A systematic search based on population, intervention, comparison, and outcome strategy was performed.
METHODS
PubMed, Scopus, and Web of Science were searched for English articles of human patients with type 1 and type 2 diabetes and contrast sensitivity measurements as domain studied.
RESULTS
Twentyone comparative cross-sectional studies were included. All of them showed significant loss of contrast sensitivity in people with diabetes and diabetic retinopathy regarding control patients of the same age, regardless of the method used. However, those without diabetic retinopathy, involve a loss of contrast sensitivity, although not always significant.
CONCLUSION
Changes in contrast sensitivity suggest that there is damage to the retina prior to the vascular ones and that they could be detected by this test.
引言
本系统评价的目的是研究糖尿病患者的对比敏感度评估是否可作为早期检测糖尿病视网膜病变的可靠测试。基于人群、干预措施、对照和结局策略进行了系统检索。
方法
在PubMed、Scopus和Web of Science中检索有关1型和2型糖尿病人类患者以及作为研究领域的对比敏感度测量的英文文章。
结果
纳入了21项比较性横断面研究。所有研究均表明，与同龄对照患者相比，糖尿病患者和糖尿病视网膜病变患者的对比敏感度均有显著下降，无论采用何种方法。然而，那些没有糖尿病视网膜病变的患者，对比敏感度也会下降，尽管并不总是显著。
结论
对比敏感度的变化表明，视网膜在血管病变之前就已受损，并且可以通过该测试检测到。
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