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妊娠期糖尿病患者的妊娠结局与护理模式的关系:一项回顾性队列研究。

Pregnancy outcomes in women with gestational diabetes mellitus by models of care: a retrospective cohort study.

机构信息

Reproduction and Perinatal Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.

Westmead Institute for Maternal & Fetal Medicine, Westmead Hospital, Westmead, New South Wales, Australia.

出版信息

BMJ Open. 2022 Sep 26;12(9):e065063. doi: 10.1136/bmjopen-2022-065063.

Abstract

OBJECTIVE

To compare birth outcomes of women with gestational diabetes mellitus (GDM) with background obstetric population, stratified by models of care.

DESIGN

Retrospective cohort study.

SETTING

A tertiary referral centre in Sydney, Australia.

PARTICIPANTS

All births 1 January 2018 to 30 November 2020. Births <24 weeks, multiple gestations and women with pre-existing diabetes were excluded.

METHODS

Data were obtained from electronic medical records. Women were classified according to GDM status and last clinic attended prior to delivery. Model of care included attendance at dedicated GDM obstetric clinics, and routine antenatal care.

MAIN OUTCOME MEASURES

Hypertensive disorders of pregnancy (HDP), pre-term birth (PTB), induction of labour (IOL), operative delivery, small for gestational age (SGA), large for gestational age, postpartum haemorrhage, obstetric anal sphincter injury (OASIS), neonatal hypoglycaemia, neonatal hypothermia, neonatal respiratory distress, neonatal intensive care unit (NICU) admission.

RESULTS

The GDM rate was 16.3%, with 34.0% of women managed in dedicated GDM clinics. Women with GDM had higher rates of several adverse outcomes. Only women with GDM attending non-dedicated clinics had increased odds of HDP (adjusted OR (adj OR) 1.6, 95% CI 1.2 to 2.0), PTB (adj OR 1.7, 95% CI 1.4 to 2.0), OASIS (adj OR 1.4, 95% CI 1.0 to 2.0), similar odds of induction (adj OR 1.0, 95% CI 0.9 to 1.1) compared with non-GDM women. There were increased odds of NICU admission (adj OR 1.5, 95% CI 1.3 to 1.8) similar to women attending high-risk GDM clinics.

CONCLUSIONS

Women with GDM receiving care in lower risk clinics had similar or higher rates of adverse outcomes. Pathways of care need to be similar in all women with GDM.

摘要

目的

比较患有妊娠糖尿病(GDM)的女性与背景产科人群的分娩结局,并按护理模式进行分层。

设计

回顾性队列研究。

地点

澳大利亚悉尼的一家三级转诊中心。

参与者

2018 年 1 月 1 日至 2020 年 11 月 30 日期间所有分娩的产妇。排除分娩<24 周、多胎妊娠和患有糖尿病的产妇。

方法

数据来自电子病历。根据 GDM 状态和分娩前最后一次就诊情况对产妇进行分类。护理模式包括参加专门的 GDM 产科诊所和常规产前护理。

主要结局测量指标

妊娠高血压疾病(HDP)、早产(PTB)、引产(IOL)、剖宫产、小于胎龄儿(SGA)、大于胎龄儿、产后出血、产科肛门括约肌损伤(OASIS)、新生儿低血糖、新生儿低体温、新生儿呼吸窘迫、新生儿重症监护病房(NICU)入住。

结果

GDM 发生率为 16.3%,其中 34.0%的产妇在专门的 GDM 诊所就诊。患有 GDM 的产妇发生多种不良结局的风险更高。仅在非专用诊所就诊的 GDM 产妇发生 HDP 的可能性更高(校正比值比(adj OR)1.6,95%置信区间 1.2 至 2.0)、PTB(adj OR 1.7,95%CI 1.4 至 2.0)、OASIS(adj OR 1.4,95%CI 1.0 至 2.0),与非 GDM 产妇相比,催产的可能性相似(adj OR 1.0,95%CI 0.9 至 1.1)。NICU 入住的可能性更高(adj OR 1.5,95%CI 1.3 至 1.8),与接受高危 GDM 诊所治疗的产妇相似。

结论

在低风险诊所接受治疗的 GDM 产妇的不良结局发生率相似或更高。所有 GDM 产妇的护理途径都应相似。

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