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发达国家新生儿重症监护病房中耐甲氧西林金黄色葡萄球菌的爆发:快速发现感染源和实施干预措施的重要性。

MRSA outbreak in a Neonatal Intensive Care Unit in a developed country: importance of rapid detection of reservoirs and implementation of intervention measures.

机构信息

Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, São Paulo, São Paulo, Brazil.

Universidade de São Paulo, Faculdade de Medicina, Instituto de Medicina Tropical de São Paulo, Laboratório de Investigação Médica em Protozoologia, Bacteriologia e Resistência Antimicrobiana (LIM-49), São Paulo, São Paulo, Brazil.

出版信息

Rev Inst Med Trop Sao Paulo. 2022 Sep 30;64:e58. doi: 10.1590/S1678-9946202264058. eCollection 2022.

Abstract

We described a MRSA bloodstream infection outbreak that was rapidly identified and controlled in a Neonatal Intensive Care Unit after implementation of a bundle of measures, including PCR-screening and HCW decolonization. We found 35% of healthcare workers(HCW) colonized with S. aureus by PCR, one of them that presented skin lesion positive for MSSA (same clone and spa type than two patients). Our findings raise the hypothesis that the outbreak could be related to HCW colonization.

摘要

我们描述了一起 MRSA 血流感染暴发事件,该事件在实施了一系列措施(包括 PCR 筛查和医护人员去定植)后,在新生儿重症监护病房迅速得到识别和控制。我们发现 35%的医护人员(HCW)通过 PCR 定植了金黄色葡萄球菌,其中一人的皮肤损伤处检测到 MSSA 阳性(与两名患者的克隆和 spa 类型相同)。我们的发现提出了这样一种假设,即暴发可能与 HCW 定植有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db03/9528307/e1a84ad96650/1678-9946-rimtsp-64-S1678-9946202264058-gf01.jpg

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