School of Nursing, Nanjing Medical University, Nanjing, China.
Department of General Surgery, Peking Union Medical College Hospital, Beijing, China.
BMJ Open. 2022 Oct 14;12(10):e064153. doi: 10.1136/bmjopen-2022-064153.
Exercise interventions are important non-pharmacological interventions for patients with mild cognitive impairment (MCI), but patients with MCI have poor compliance and there is no consistent strategy for exercise interventions. Understanding the needs and preferences of MCI patients allows for the development of effective and acceptable exercise intervention programmes that achieve the goals of patient-centred care. This study uses a discrete choice experiment (DCE) to measure and quantify MCI patients' preferences for exercise interventions, and aims at (1) identifying and exploring which elements of exercise intervention programmes are essential for MCI patients; (2) measuring MCI patients' preferences for exercise interventions and summarising relevant characteristics that may influence preference choices and (3) determining whether these preferences vary by participant characteristics and classifying the population types based on the sociodemographic characteristics of the participants.
A DCE will be conducted to explore MCI patients' preferences for exercise interventions. We conducted a systematic literature review and extensive qualitative work to select the best attributes to develop the design of DCE. A partial factorial survey design was generated through an orthogonal experimental design. We will conduct a questionnaire survey in one city each in the eastern (Nanjing), western (Xining), southern (Zhuhai) and northern (Beijing) parts of China and reach the planned sample size (n=278). Final data will be analysed using a mixed logit model and a latent class model.
This study was approved by the Ethics Committee of Nanjing Medical University (2021-666). All participants will be required to provide informed consent. Our findings will be disseminated and shared with interested patient groups and the general public through online blogs, policy briefs, national and international conferences and peer-reviewed journals.
运动干预对于轻度认知障碍(MCI)患者来说是重要的非药物干预措施,但 MCI 患者的依从性较差,且运动干预措施也没有统一的策略。了解 MCI 患者的需求和偏好,可以制定出有效且可接受的运动干预计划,从而实现以患者为中心的护理目标。本研究使用离散选择实验(DCE)来衡量和量化 MCI 患者对运动干预的偏好,并旨在:(1)确定和探讨运动干预计划中对 MCI 患者必不可少的要素;(2)测量 MCI 患者对运动干预的偏好,并总结可能影响偏好选择的相关特征;(3)确定这些偏好是否因参与者特征而异,并根据参与者的社会人口学特征对人群类型进行分类。
将进行 DCE 以探索 MCI 患者对运动干预的偏好。我们进行了系统的文献回顾和广泛的定性工作,以选择最佳属性来制定 DCE 的设计。通过正交实验设计生成部分因子调查设计。我们将在中国东部(南京)、西部(西宁)、南部(珠海)和北部(北京)的每个城市进行问卷调查,达到计划的样本量(n=278)。最终数据将使用混合 logit 模型和潜在类别模型进行分析。
本研究已获得南京医科大学伦理委员会的批准(2021-666)。所有参与者都将被要求提供知情同意书。我们的研究结果将通过在线博客、政策简报、国家和国际会议以及同行评议期刊与有兴趣的患者群体和公众进行传播和共享。