Adlhoch Cornelia, Fusaro Alice, Gonzales José L, Kuiken Thijs, Marangon Stefano, Niqueux Éric, Staubach Christoph, Terregino Calogero, Guajardo Irene Muñoz, Chuzhakina Kateryna, Baldinelli Francesca
EFSA J. 2022 Oct 11;20(10):e07597. doi: 10.2903/j.efsa.2022.7597. eCollection 2022 Oct.
The 2021-2022 highly pathogenic avian influenza (HPAI) epidemic season is the largest HPAI epidemic so far observed in Europe, with a total of 2,467 outbreaks in poultry, 47.7 million birds culled in the affected establishments, 187 outbreaks in captive birds, and 3,573 HPAI virus detections in wild birds with an unprecedent geographical extent reaching from Svalbard islands to South Portugal and Ukraine, affecting 37 European countries. Between 11 June and 9 September 2022, 788 HPAI virus detections were reported in 16 European countries in poultry (56), captive (22) and wild birds (710). Several colony-breeding seabird species exhibited widespread and massive mortality from HPAI A(H5N1) virus along the northwest coast of Europe. This resulted in an unprecedentedly high level of HPAI virus detections in wild birds between June and August 2022 and represents an ongoing risk of infection for domestic birds. HPAI outbreaks were still observed in poultry from June to September with five-fold more infected premises than observed during the same period in 2021 and mostly distributed along the Atlantic coast. Response options to this new epidemiological situation include the definition and rapid implementation of suitable and sustainable HPAI mitigation strategies such as appropriate biosecurity measures and surveillance strategies for early detection in the different poultry production systems. The viruses currently circulating in Europe belong to clade 2.3.4.4b with seven genotypes, three of which identified for the first time during this time period, being detected during summer. HPAI A(H5) viruses were also detected in wild mammal species in Europe and North America and showed genetic markers of adaptation to replication in mammals. Since the last report, two A(H5N6), two A(H9N2) and one A(H10N3) human infections were reported in China. The risk of infection is assessed as low for the general population in the EU/EEA, and low to medium for occupationally exposed people.
2021 - 2022年高致病性禽流感(HPAI)流行季是欧洲迄今观测到的最大规模的HPAI疫情,家禽中共有2467起疫情,受影响场所扑杀了4770万只禽鸟,圈养鸟类中有187起疫情,野生鸟类中有3573次检测到HPAI病毒,地理范围空前广泛,从斯瓦尔巴群岛延伸至葡萄牙南部和乌克兰,影响了37个欧洲国家。2022年6月11日至9月9日期间,16个欧洲国家在家禽(56起)、圈养鸟类(22起)和野生鸟类(710起)中报告了788次HPAI病毒检测结果。几种集群繁殖海鸟物种在欧洲西北海岸因HPAI A(H5N1)病毒出现了广泛而大量的死亡。这导致2022年6月至8月期间野生鸟类中HPAI病毒检测水平空前高,并对家禽构成持续感染风险。6月至9月在家禽中仍观察到HPAI疫情,感染场所数量是2021年同期的五倍,且大多分布在大西洋沿岸。针对这一新的流行病学情况的应对选项包括定义并迅速实施适当且可持续的HPAI缓解策略,如不同家禽生产系统中的适当生物安全措施和早期检测监测策略。目前在欧洲传播的病毒属于2.3.4.4b分支,有七种基因型,其中三种在此期间首次被鉴定出来,是在夏季检测到的。在欧洲和北美的野生哺乳动物物种中也检测到了HPAI A(H5)病毒,并显示出适应在哺乳动物中复制的基因标记。自上次报告以来,中国报告了两例A(H5N6)、两例A(H9N2)和一例A(H10N3)人类感染病例。欧盟/欧洲经济区普通人群的感染风险评估为低,职业暴露人群的感染风险评估为低到中等。