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MRI 在格雷夫斯眼病中的应用研究进展。

Current insights of applying MRI in Graves' ophthalmopathy.

机构信息

Department of Endocrinology and Metabolism, Shunde Hospital of Southern Medical University (The First People's Hospital of Shunde), Foshan, China.

The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

出版信息

Front Endocrinol (Lausanne). 2022 Sep 29;13:991588. doi: 10.3389/fendo.2022.991588. eCollection 2022.

Abstract

Graves' ophthalmopathy (GO) is an autoimmune disease related to Grave's disease (GD). The therapeutic strategies for GO patients are based on precise assessment of the activity and severity of the disease. However, the current assessment systems require development to accommodate updates in treatment protocols. As an important adjunct examination, magnetic resonance imaging (MRI) can help physicians evaluate GO more accurately. With the continuous updating of MRI technology and the deepening understanding of GO, the assessment of this disease by MRI has gone through a stage from qualitative to precise quantification, making it possible for clinicians to monitor the microstructural changes behind the eyeball and better integrate clinical manifestations with pathology. In this review, we use orbital structures as a classification to combine pathological changes with MRI features. We also review some MRI techniques applied to GO clinical practice, such as disease classification and regions of interest selection.

摘要

格雷夫斯眼病(GO)是一种与格雷夫斯病(GD)相关的自身免疫性疾病。GO 患者的治疗策略基于对疾病活动度和严重程度的精确评估。然而,目前的评估系统需要进一步发展,以适应治疗方案的更新。作为一种重要的辅助检查,磁共振成像(MRI)可以帮助医生更准确地评估 GO。随着 MRI 技术的不断更新和对 GO 的深入了解,MRI 对该病的评估已经经历了从定性到精确定量的阶段,使临床医生能够监测眼球背后的微观结构变化,并更好地将临床表现与病理学相结合。在这篇综述中,我们使用眼眶结构作为分类,将病理变化与 MRI 特征相结合。我们还回顾了一些应用于 GO 临床实践的 MRI 技术,如疾病分类和感兴趣区选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd51/9577927/32e14a2c0a20/fendo-13-991588-g001.jpg

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