肾脏对镁的处理

Renal handling of magnesium.

作者信息

Dirks J H, Quamme G A

出版信息

Adv Exp Med Biol. 1978;103:51-64. doi: 10.1007/978-1-4684-7758-0_5.

Abstract

In summary, magnesium reabsorption occurs throughout the proximal and distal segments of the nephron. The proximal tubule is less permeable to magnesium than calcium and sodium with most of the filtered load being reclaimed in the ascending loop of Henle. In contrast to calcium and sodium a tubular reabsorptive maximum has been demonstrated for magnesium and under certain circumstances secretion has been demonstrated in the terminal nephron segments. Although many factors are known to affect magnesium reabsorption the mechanism of the renal homeostasis remains to be determined.

摘要

总之，镁的重吸收发生在整个肾单位的近端和远端节段。近端小管对镁的通透性低于钙和钠，大部分滤过负荷在髓袢升支被重吸收。与钙和钠不同，已证实镁存在肾小管重吸收最大值，并且在某些情况下，终末肾单位节段会出现分泌现象。尽管已知许多因素会影响镁的重吸收，但肾脏内稳态的机制仍有待确定。