Sparić Radmila, Andjić Mladen, D'Oria Ottavia, Babović Ivana, Milovanović Zagorka, Panese Gaetano, Licchelli Martina, Tomašević Đina, Morciano Andrea, Tinelli Andrea
Clinic for Gynecology and Obstetrics, University Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Clinic for Gynecology and Obstetrics, University Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Healthcare (Basel). 2022 Oct 19;10(10):2087. doi: 10.3390/healthcare10102087.
The authors reviewed uterine fibroid (UF) morcellation and its potential consequences, notably a hypothetical spread and dissemination of occult uterine leiomyosarcoma (LMS) tissue, evaluating the effect of laparoscopic versus open myomectomies with and without morcellation on patients' outcomes, as well as related medical-legal issues. MEDLINE and PubMed search was performed for the years 1990-2021, using a combination of keywords on this topic. Relevant articles were identified and included in this narrative review. There is an individual risk, for all patients, for LMS diagnosis after myomectomy. However, the risk for occult LMS diagnosis during a laparoscopic myomectomy is generally reduced when the guidelines of scientific societies are followed, with an overall benefit from the laparoscopic approach with morcellation in appropriate cases. Gynecological societies do not ban morcellation and laparoscopic hysterectomy/myomectomy per se, but recommend their use on the basis of the patients' clinical characteristics. It is suggested for gynecologists to provide detailed information to patients when obtaining an informed consent for open or laparoscopic hysterectomy/myomectomy. A detailed preoperative assessment of patients and the risk benefit ratio of laparoscopic morcellation of uterine mass could overcome the "a priori" banning of the morcellation technique.
作者回顾了子宫肌瘤(UF)粉碎术及其潜在后果,尤其是隐匿性子宫平滑肌肉瘤(LMS)组织的假想播散,评估了腹腔镜下肌瘤切除术与开腹肌瘤切除术在有或无粉碎术情况下对患者预后的影响,以及相关的医疗法律问题。使用关于该主题的关键词组合,对1990年至2021年期间的MEDLINE和PubMed进行了检索。识别出相关文章并纳入本叙述性综述。对所有患者而言,肌瘤切除术后都存在LMS诊断的个体风险。然而,遵循科学学会的指南时,腹腔镜肌瘤切除术中隐匿性LMS诊断的风险通常会降低,在适当情况下,腹腔镜粉碎术方法总体上有好处。妇科协会并不禁止粉碎术和腹腔镜子宫切除术/肌瘤切除术本身,但建议根据患者的临床特征使用。建议妇科医生在为患者进行开腹或腹腔镜子宫切除术/肌瘤切除术获取知情同意时,向患者提供详细信息。对患者进行详细的术前评估以及子宫肿物腹腔镜粉碎术的风险效益比,可能会克服对粉碎术技术的“先验”禁令。