Department of Dental Surgery, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Pl. Akademicki 17, 41-902 Bytom, Poland.
Department of Conservative Dentistry with Endodontics, Faculty of Medical Science, Medical University of Silesia, Pl. Akademicki 17, 41-902 Bytom, Poland.
Int J Environ Res Public Health. 2022 Dec 2;19(23):16151. doi: 10.3390/ijerph192316151.
The development of medicine is based not only on the introduction of new methods of treatment, but also on the use of increasingly effective drugs, including antithrombotic drugs. Drugs that inhibit the activity of platelets (antiplatelet and anti-aggregating drugs) and pharmaceuticals that inhibit the activity of plasma coagulation factors (anticoagulants) are used in antithrombotic therapy. In our daily practice we encounter patients who take chronic antiplatelet or anticoagulant drugs. However, more and more often we are dealing with patients who are treated with two antiplatelet drugs, an antiplatelet and an anticoagulant or even undergoing triple antithrombotic therapy. When preparing the patient for invasive craniofacial procedures, it should be assessed whether the temporary discontinuation of antithrombotic treatment due to the fear of excessive perioperative bleeding is justified and will not result in life-threatening thromboembolic complications. The authors discuss in detail the medications used in modern antithrombotic treatment and present a perioperative management procedure with a patient who takes l4 z of these medications chronically.
医学的发展不仅基于新的治疗方法的引入,还基于越来越有效的药物的使用,包括抗血栓药物。抗血栓治疗中使用抑制血小板活性(抗血小板和抗聚集药物)和抑制血浆凝血因子活性的药物(抗凝剂)。在我们的日常实践中,我们遇到服用慢性抗血小板或抗凝药物的患者。然而,我们越来越经常遇到同时服用两种抗血小板药物、一种抗血小板药物和一种抗凝剂甚至接受三联抗血栓治疗的患者。在为接受侵入性颅面手术的患者做准备时,应评估由于担心过度围手术期出血而暂时停止抗血栓治疗是否合理,并且不会导致危及生命的血栓栓塞并发症。作者详细讨论了现代抗血栓治疗中使用的药物,并介绍了一位长期服用这些药物的患者的围手术期管理程序。