Antibiotic Resistance of spp. Isolated from the Urine of Patients Hospitalized in the University Hospital in North-Central Poland, 2016-2021.

Urinary Tract Infections (UTIs) are common outpatient and inpatient infections, often treated with empirical therapy. spp. is responsible for about 10% of UTIs. This study aimed to determine the necessity of changing the empirical treatment of UTIs caused by spp. The evaluation was performed for 542 strains isolated from urine samples in the years 2016-2021. We identified three species that were found: (389, 71.8%), (151, 27.8%) and (2, 0.4%). was the dominant species every year. Among the most prevalent was resistance to norfloxacin (51.4%). Almost all strains (150, 99.3%) were resistant to beta-lactams and norfloxacin. Eighty-three strains (55.0%) were resistant to vancomycin and 72 (47.7%) to teicoplanin. strains showed a significantly higher percentage of resistance mechanisms GRE (Glicopeptide-Resistant ) (72, 48.7%) and VRE (Vancomycin-Resistant ) (11, 7.3%), while only five strains of showed a VRE mechanism (1.3%). In the therapy of UTIs, ampicillin and imipenem still remain effective. However, the above-mentioned antibiotics, as well as fluoroquinolones, are not recommended in the treatment of UTIs of etiology.