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腹壁下动脉穿支皮瓣乳房重建术:双侧与单侧重建的发病率研究。

DIEP flap in breast reconstruction: A morbidity study of bilateral versus unilateral reconstruction.

机构信息

Department of Plastic and Reconstructive Surgery,University of Montreal Health Care Center (CHUM), Montreal, Québec, Canada.

Department of Plastic and Reconstructive Surgery,University of Montreal Health Care Center (CHUM), Montreal, Québec, Canada.

出版信息

Ann Chir Plast Esthet. 2023 Aug;68(4):300-307. doi: 10.1016/j.anplas.2022.12.003. Epub 2023 Jan 13.

Abstract

BACKGROUND

The Deep Inferior Epigastric Perforator (DIEP) flap is a modality in breast reconstruction of choice. Despite its well-documented benefits and complications, a lack of evidence remains with regards to the risks of performing a bilateral versus a unilateral reconstruction. As such, we sought to compare the rates of adverse outcomes in the perioperative and postoperative periods associated with a unilateral versus a bilateral DIEP flap breast reconstruction.

METHODS

A retrospective cohort study of 178 consecutive patients undergoing unilateral versus. bilateral deep inferior epigastric perforator flap breast reconstruction was performed at our tertiary care center over a 3-year period. Data on demographics, operative time, intraoperative and postoperative complications, and surgical re-exploration, were extracted for both groups. Statistical analysis was performed on a per-flap basis.

RESULTS

A total of 157 unilateral and 42 bilateral deep inferior epigastric perforator flaps were identified. The rate of intra-operative complications was 12.1% for unilateral versus. 4.8% for bilateral flaps (P=0.26). Total post-operative complications rates were 30.6% for unilateral versus 54.7% for bilateral flaps (P=0.003). Surgical re-exploration was performed in 12.7% of unilateral and 11.9% of bilateral cases (P=0.88). The rate of total flap loss was similar between types of reconstruction, occurring in 2.5% of unilateral vs. 2.4% of bilateral flaps (P=1).

CONCLUSION

This study demonstrates the rate of complications per flap is significantly higher in bilateral versus unilateral deep inferior epigastric perforator flap breast reconstruction. Bilateral DIEP breast reconstruction should be decided on a case-by-case basis.

LEVEL OF EVIDENCE

Prognostic/Risk Study, Level II.

摘要

背景

深下腹壁穿支皮瓣(DIEP)是乳房重建的首选方式。尽管它的益处和并发症已被充分记录,但在双侧与单侧重建相关的风险方面仍缺乏证据。因此,我们旨在比较单侧与双侧 DIEP 皮瓣乳房重建术相关的围手术期和术后不良结局的发生率。

方法

对 3 年来在我们的三级护理中心接受单侧与双侧深下腹壁穿支皮瓣乳房重建的 178 例连续患者进行了回顾性队列研究。对两组患者的人口统计学数据、手术时间、术中及术后并发症以及手术再次探查进行了数据提取。对每个皮瓣进行了统计学分析。

结果

共发现 157 个单侧和 42 个双侧深下腹壁穿支皮瓣。单侧皮瓣的术中并发症发生率为 12.1%,而双侧皮瓣为 4.8%(P=0.26)。单侧皮瓣的总术后并发症发生率为 30.6%,而双侧皮瓣为 54.7%(P=0.003)。单侧皮瓣中有 12.7%需要进行手术再次探查,而双侧皮瓣中有 11.9%需要进行手术再次探查(P=0.88)。两种重建类型的总皮瓣失效率相似,单侧为 2.5%,双侧为 2.4%(P=1)。

结论

本研究表明,双侧 DIEP 皮瓣乳房重建的皮瓣并发症发生率明显高于单侧。双侧 DIEP 乳房重建应根据具体情况决定。

证据水平

预后/风险研究,II 级。

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