PSMA PET/CT时代前列腺癌根治术后复发性前列腺癌患者盆腔淋巴结照射的必要性：一项叙述性综述
Necessity of Pelvic Lymph Node Irradiation in Patients with Recurrent Prostate Cancer after Radical Prostatectomy in the PSMA PET/CT Era: A Narrative Review.
作者信息
Nabian Naeim, Ghalehtaki Reza, Couñago Felipe
机构信息
Radiation Oncology Research Center, Cancer Research Institute, Tehran University of Medical Sciences, Tehran P.O. Box 1419733141, Iran.
Department of Radiation Oncology, Cancer Institute, Tehran University of Medical Sciences, Tehran P.O. Box 1419733141, Iran.
出版信息
Biomedicines. 2022 Dec 24;11(1):38. doi: 10.3390/biomedicines11010038.
The main prostate cancer (PCa) treatments include surgery or radiotherapy (with or without ADT). However, none of the suggested treatments eliminates the risk of lymph node metastases. Conventional imaging methods, including MRI and CT scanning, are not sensitive enough for the diagnosis of lymph node metastases; however, the novel imaging method, PSMA PET/CT scanning, has provided valuable information about the pelvic LN involvement in patients with recurrent PCa (RPCa) after radical prostatectomy. The high sensitivity and negative predictive value enable accurate N staging in PCa patients. In this narrative review, we summarize the evidence on the treatment and extent of radiation in prostate-only or whole-pelvis radiation in patients with positive and negative LN involvement on PSMA PET/CT scans.
主要的前列腺癌（PCa）治疗方法包括手术或放疗（联合或不联合雄激素剥夺治疗[ADT]）。然而，所建议的治疗方法均无法消除淋巴结转移的风险。包括MRI和CT扫描在内的传统成像方法对淋巴结转移的诊断不够敏感；然而，新型成像方法——前列腺特异性膜抗原（PSMA）PET/CT扫描，为根治性前列腺切除术后复发性PCa（RPCa）患者盆腔淋巴结受累情况提供了有价值的信息。其高敏感性和阴性预测值能够对PCa患者进行准确的N分期。在这篇叙述性综述中，我们总结了PSMA PET/CT扫描显示淋巴结受累阳性和阴性的患者在仅前列腺放疗或全盆腔放疗的治疗及放疗范围方面的证据。
Zotero 插件