Suppr超能文献

铁、锌、铜、镉、汞与骨组织。

Iron, Zinc, Copper, Cadmium, Mercury, and Bone Tissue.

机构信息

Chair and Department of Medical Rehabilitation and Clinical Physiotherapy, Pomeranian Medical University in Szczecin, Żołnierska 54, 70-210 Szczecin, Poland.

Department of Biology and Medical Parasitology, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.

出版信息

Int J Environ Res Public Health. 2023 Jan 26;20(3):2197. doi: 10.3390/ijerph20032197.

Abstract

The paper presents the current understanding on the effects of five metals on bone tissue, namely iron, zinc, copper, cadmium, and mercury. Iron, zinc, and copper contribute significantly to human and animal metabolism when present in sufficient amounts, but their excess or shortage increases the risk of developing bone disorders. In contrast, cadmium and mercury serve no physiological purpose and their long-term accumulation damages the osteoarticular system. We discuss the methods of action and interactions between the discussed elements as well as the concentrations of each element in distinct bone structures.

摘要

本文介绍了目前人们对五种金属(铁、锌、铜、镉和汞)对骨骼组织影响的认识。在适量存在的情况下,铁、锌和铜对人体和动物的新陈代谢有重要贡献,但过量或缺乏会增加骨骼疾病的风险。相比之下,镉和汞没有生理作用,它们的长期积累会损害骨-关节系统。我们讨论了所讨论元素的作用方式和相互作用,以及每个元素在不同骨骼结构中的浓度。

相似文献

1
Iron, Zinc, Copper, Cadmium, Mercury, and Bone Tissue.
Int J Environ Res Public Health. 2023 Jan 26;20(3):2197. doi: 10.3390/ijerph20032197.
4
Comparison of metal concentrations in bones of long-living mammals.
Biol Trace Elem Res. 2013 May;152(2):195-203. doi: 10.1007/s12011-013-9615-x. Epub 2013 Feb 2.
5
Effect of zinc, cadmium or copper on mercury distribution in rat tissues.
Toxicol Lett. 1983 Jul;17(3-4):349-54. doi: 10.1016/0378-4274(83)90249-7.
9
Interactions of cadmium with copper, iron, zinc, and manganese in ovine tissues.
J Nutr. 1975 May;105(5):599-606. doi: 10.1093/jn/105.5.599.
10
Interactions of cadmium with copper, zinc and iron in different organs and tissues of the rat.
Acta Pharmacol Toxicol (Copenh). 1977 Nov;41(5):515-24. doi: 10.1111/j.1600-0773.1977.tb02163.x.

引用本文的文献

4
Copper metabolism in hepatocellular carcinoma: from molecular mechanisms to therapeutic opportunities.
Front Mol Biosci. 2025 May 13;12:1578693. doi: 10.3389/fmolb.2025.1578693. eCollection 2025.
6
Mercury Exposure and Health Effects: What Do We Really Know?
Int J Mol Sci. 2025 Mar 5;26(5):2326. doi: 10.3390/ijms26052326.
9
Association of per- and polyfluoroalkylated substances/heavy metals and bone health in children and adolescents.
Front Public Health. 2024 Oct 10;12:1431001. doi: 10.3389/fpubh.2024.1431001. eCollection 2024.
10
Copper metabolism in osteoarthritis and its relation to oxidative stress and ferroptosis in chondrocytes.
Front Mol Biosci. 2024 Sep 11;11:1472492. doi: 10.3389/fmolb.2024.1472492. eCollection 2024.

本文引用的文献

2
Copper as Dietary Supplement for Bone Metabolism: A Review.
Nutrients. 2021 Jun 29;13(7):2246. doi: 10.3390/nu13072246.
3
Natural incorporation of mercury in bone.
J Trace Elem Med Biol. 2021 Sep;67:126797. doi: 10.1016/j.jtemb.2021.126797. Epub 2021 May 28.
4
The Effects of Calcium, Magnesium, Phosphorus, Fluoride, and Lead on Bone Tissue.
Biomolecules. 2021 Mar 28;11(4):506. doi: 10.3390/biom11040506.
5
Influence of Cu on Osteoclast Formation and Activity In Vitro.
Int J Mol Sci. 2021 Feb 28;22(5):2451. doi: 10.3390/ijms22052451.
6
The role of TGF-β1/Smad3 signaling pathway and oxidative stress in the inhibition of osteoblast mineralization by copper chloride.
Environ Toxicol Pharmacol. 2021 May;84:103613. doi: 10.1016/j.etap.2021.103613. Epub 2021 Feb 8.
7
Adverse Impact of Heavy Metals on Bone Cells and Bone Metabolism Dependently and Independently through Anemia.
Adv Sci (Weinh). 2020 Aug 4;7(19):2000383. doi: 10.1002/advs.202000383. eCollection 2020 Oct.
8
The Role of Fe, Zn, and Cu in Pregnancy.
Biomolecules. 2020 Aug 12;10(8):1176. doi: 10.3390/biom10081176.
9
The Effects of Cadmium Toxicity.
Int J Environ Res Public Health. 2020 May 26;17(11):3782. doi: 10.3390/ijerph17113782.
10
Zinc as a Therapeutic Agent in Bone Regeneration.
Materials (Basel). 2020 May 12;13(10):2211. doi: 10.3390/ma13102211.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验