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儿童克罗恩病排除饮食治疗一年后饮食习惯的改变。

Dietary Habit Modifications in Paediatric Patients after One Year of Treatment with the Crohn's Disease Exclusion Diet.

机构信息

Paediatric Gastroenterology and Nutrition Unit, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.

出版信息

Nutrients. 2023 Jan 20;15(3):554. doi: 10.3390/nu15030554.

Abstract

Gut microbiota alterations play a key role in the pathogenesis of inflammatory bowel disease (IBD), and its modification through specific diets is an emerging line of treatment that is currently being researched. The aim of this study was to assess changes in the dietary habits of patients with Crohn's disease (CD) and their long-term adherence to dietary therapy with the Crohn's disease exclusion diet (CDED) after one year. To analyse the modification of dietary habits and adherence to the Mediterranean diet (DM), the KIDMED questionnaire, a food consumption frequency questionnaire, was used. Twenty-four hour recalls at two timepoints, namely prior to the start of the dietary therapy and one year later, were also carried out. The processing degrees of the foods consumed by the patients were analysed at both timepoints using the NOVA classification system. Data from 24 patients (15 boys), with a mean age of 12.7 ± 2.9 years at the start of the dietary therapy, were analysed. All patients showed an improvement in their dietary pattern in the form of a reduction in the intake of ultra-processed foods (UPFs); a higher adherence to the MD; a decrease in the intake of cold meats, seafood, pasta, precooked foods, soft drinks, and pastries; an increase in the intake of eggs, legumes, dairy products, and nuts ( < 0.05); and adequate adherence, even in the long-term, to foods allowed during the different phases of the dietary regimen. Although more factors have an impact on the course of the disease in these patients, improving their dietary habits is essential.

摘要

肠道微生物群的改变在炎症性肠病 (IBD) 的发病机制中起着关键作用,通过特定饮食来改变肠道微生物群是一种新兴的治疗方法,目前正在研究中。本研究旨在评估克罗恩病 (CD) 患者饮食习惯的变化及其对克罗恩病排除饮食 (CDED) 的长期饮食治疗的依从性,为期一年。为了分析饮食习惯的改变和对地中海饮食 (DM) 的依从性,使用了 KIDMED 问卷,这是一种食物消费频率问卷。在两个时间点(即开始饮食治疗之前和一年后)还进行了 24 小时回忆。使用 NOVA 分类系统分析患者在这两个时间点所食用食物的加工程度。分析了 24 名患者(15 名男孩)的数据,这些患者在开始饮食治疗时的平均年龄为 12.7 ± 2.9 岁。所有患者的饮食模式都有所改善,表现为减少了超加工食品 (UPFs) 的摄入;对 MD 的依从性更高;减少了冷肉、海鲜、意大利面、预煮食品、软饮料和糕点的摄入;增加了鸡蛋、豆类、乳制品和坚果的摄入(<0.05);并且即使在长期内,也能适当遵循饮食方案不同阶段允许的食物。尽管在这些患者中,有更多的因素影响疾病的进程,但改善他们的饮食习惯是至关重要的。

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