Ranjitha Y S, Shetty Anita N, Hemantkumar Indrani, Gangakhedkar Gauri R, Choudhari Ashwini
Department of Anaesthesiology and Critical Care, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India.
J Anaesthesiol Clin Pharmacol. 2022 Oct-Dec;38(4):594-598. doi: 10.4103/joacp.JOACP_638_20. Epub 2022 Jun 15.
Blood loss in neurosurgical procedures can be rapid and tremendous leading to consequential hemodynamic instability. HemoCue is a portable photometer used for the measurement of blood hemoglobin concentration. Using this point of care device, we contemplated this study to assess the reliability of HemoCue for suction hemoglobin determination and calculation of surgical blood loss by comparing with the gold standard laboratory Coulter Counter method in patients undergoing neurosurgical procedures.
This prospective observational study was conducted in 233 patients undergoing elective neurosurgical procedures in the age group of 18 to 60 years and having preoperative hemoglobin (Hb) values above 9 g/dL. Values of preoperative hemoglobin, suction hemoglobin, and volume in the suction container were used to obtain the estimated blood loss. The normality of the data was tested using the Kolmogorov Smirnov test. Bland Altman analysis was used to test the reliability of HemoCue in estimating hemoglobin and blood loss with reference to the gold standard laboratory Coulter Counter automated hematology analyzer.
Median blood loss calculated in our study using HemoCue was 554.65 mL with an interquartile range of 336.81 mL to 982.39 mL. Laboratory counter method estimated median blood loss was 533.37 mL with an interquartile range of 335.21 mL to 994.73 mL. The majority of the data obtained and analyzed using the Bland and Altman analysis method were within a 95% confidence interval.
The HemoCue method is a reliable method and henceforth can be used to estimate blood loss in suction fluid in patients undergoing neurosurgical procedures.
神经外科手术中的失血可能迅速且量大,导致随之而来的血流动力学不稳定。HemoCue是一种用于测量血液血红蛋白浓度的便携式光度计。我们设想通过这项研究,在接受神经外科手术的患者中,将HemoCue用于测定吸引物血红蛋白及计算手术失血量的可靠性与金标准实验室库尔特计数器法进行比较。
这项前瞻性观察性研究纳入了233例年龄在18至60岁、术前血红蛋白(Hb)值高于9 g/dL且接受择期神经外科手术的患者。术前血红蛋白值、吸引物血红蛋白值以及吸引容器中的血量用于获取估计失血量。使用柯尔莫哥洛夫-斯米尔诺夫检验来检验数据的正态性。采用布兰德-奥特曼分析来检验HemoCue在参照金标准实验室库尔特计数器自动血液分析仪估计血红蛋白和失血量方面的可靠性。
在我们的研究中,使用HemoCue计算的中位失血量为554.65 mL,四分位间距为336.81 mL至982.39 mL。实验室计数器法估计的中位失血量为533.37 mL,四分位间距为335.21 mL至994.73 mL。使用布兰德和奥特曼分析方法获得并分析的大多数数据在95%置信区间内。
HemoCue方法是一种可靠的方法,今后可用于估计接受神经外科手术患者吸引液中的失血量。