Department of Radiology, Pamukkale University Faculty of Medicine, Denizli, Turkey.
Department of Radiology, Ege University Faculty of Medicine, İzmir, Turkey.
Diagn Interv Radiol. 2023 Jan 31;29(1):80-90. doi: 10.5152/dir.2022.21614. Epub 2022 Nov 29.
Pulmonary adverse events and drug-induced lung disease (DILD) can occur when treating many conditions. The incidence of DILDs in clinical practice and the variety of radiological findings have increased, mainly due to the increased use of novel therapeutic agents. It is crucial to determine whether the newly emerging clinical and imaging findings in these patients are due to the progression of the underlying disease, infection, pulmonary edema, or drug use, as this will change the patient management. Although the diagnosis of DILD is usually obtained by excluding other possible causes, radiologists should be aware of the imaging findings of DILD. This article reviews the essential radiological results of DILD and summarizes the critical clinical and imaging findings with an emphasis on novel therapeutic agents.
在治疗许多疾病时,可能会出现肺部不良反应和药物性肺病(DILD)。由于新型治疗药物的广泛应用,临床实践中 DILD 的发生率和各种影像学表现均有所增加。确定这些患者新出现的临床和影像学表现是疾病进展、感染、肺水肿还是药物使用引起的至关重要,因为这将改变患者的管理方式。虽然 DILD 的诊断通常通过排除其他可能的原因来获得,但放射科医生应该了解 DILD 的影像学表现。本文回顾了 DILD 的基本放射学结果,并总结了关键的临床和影像学表现,重点介绍了新型治疗药物。