Minervini Giuseppe, Franco Rocco, Marrapodi Maria Maddalena, Mehta Vini, Fiorillo Luca, Badnjević Almir, Cervino Gabriele, Cicciù Marco
Multidisciplinary Department of Medical-Surgical and Odontostomatological Specialties, University of Campania "Luigi Vanvitelli", 80121 Naples, Italy.
Department of Biomedicine and Prevention, University of University of Rome "Tor Vergata", 00100 Rome, Italy.
Brain Sci. 2023 Mar 12;13(3):481. doi: 10.3390/brainsci13030481.
The coronavirus belongs to the family of Coronaviridae, which are not branched single-stranded RNA viruses. COVID-19 creates respiratory problems and infections ranging from mild to severe. The virus features mechanisms that serve to delay the cellular immune response. The host's response is responsible for the pathological process that leads to tissue destruction. Temporomandibular disorders are manifested by painful jaw musculature and jaw joint areas, clicks, or creaks when opening or closing the mouth. All these symptoms can be disabling and occur during chewing and when the patient yawns or even speaks. The pandemic situation has exacerbated anxieties and amplified the vulnerability of individuals. Therefore, from this mechanism, how the COVID-19 pandemic may have increased the incidence of temporomandibular disorders is perceived. The purpose of this review is to evaluate whether COVID-19-related anxiety has caused an increase in temporomandibular dysfunction symptoms in adults to children. PubMed, Web of Science, Lilacs, and Scopus were systematically searched, until 30 July 2022, to identify studies presenting: the connection between COVID-19 with temporomandibular disorders. From 198 papers, 4 studies were included. Literature studies have shown that the state of uncertainty and anxiety has led to an increase in the incidence of this type of disorder, although not all studies agree. Seventy-three studies were identified after viewing all four search engines; at the end of the screening phase, only four were considered that met the PECO, the planned inclusion, and the exclusion criteria. All studies showed a statistically significant correlation between temporomandibular disorders and COVID-19 with a < 0.05. All studies agreed that there is an association between COVID-19 and increased incidence of temporomandibular disorders.
冠状病毒属于冠状病毒科,是不分枝的单链RNA病毒。新型冠状病毒肺炎会引发从轻度到重度的呼吸道问题和感染。该病毒具有延迟细胞免疫反应的机制。宿主的反应是导致组织破坏的病理过程的原因。颞下颌关节紊乱表现为颌面部肌肉和颌关节区域疼痛、张嘴或闭嘴时有咔哒声或嘎吱声。所有这些症状都可能使人丧失能力,在咀嚼、患者打哈欠甚至说话时都会出现。疫情状况加剧了焦虑情绪,放大了个体的脆弱性。因此,从这一机制可以看出新型冠状病毒肺炎大流行可能如何增加了颞下颌关节紊乱的发病率。本综述的目的是评估与新型冠状病毒肺炎相关的焦虑是否导致了成人到儿童颞下颌关节功能障碍症状的增加。系统检索了PubMed、科学网、Lilacs和Scopus,直至2022年7月30日,以确定呈现新型冠状病毒肺炎与颞下颌关节紊乱之间联系的研究。从198篇论文中,纳入了4项研究。文献研究表明,不确定和焦虑状态导致了这类疾病发病率的上升,尽管并非所有研究都认同这一点。在查看了所有四个搜索引擎后,共识别出73项研究;在筛选阶段结束时,仅四项研究被认为符合PECO、计划纳入和排除标准。所有研究均显示颞下颌关节紊乱与新型冠状病毒肺炎之间存在统计学显著相关性,P<0.05。所有研究均认为新型冠状病毒肺炎与颞下颌关节紊乱发病率增加之间存在关联。