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传染病疫苗研发进展——基石研讨会报告。

Progress in vaccine development for infectious diseases-a Keystone Symposia report.

机构信息

PhD Science Writer, New York, New York, USA.

Morehouse School of Medicine, Atlanta, Georgia, USA.

出版信息

Ann N Y Acad Sci. 2023 Jun;1524(1):65-86. doi: 10.1111/nyas.14975. Epub 2023 Apr 5.

Abstract

The COVID-19 pandemic has taught us many things, among the most important of which is that vaccines are one of the cornerstones of public health that help make modern longevity possible. While several different vaccines have been successful at stemming the morbidity and mortality associated with various infectious diseases, many pathogens/diseases remain recalcitrant to the development of effective vaccination. Recent advances in vaccine technology, immunology, structural biology, and other fields may yet yield insight that will address these diseases; they may also help improve societies' preparedness for future pandemics. On June 1-4, 2022, experts in vaccinology from academia, industry, and government convened for the Keystone symposium "Progress in Vaccine Development for Infectious Diseases" to discuss state-of-the-art technologies, recent advancements in understanding vaccine-mediated immunity, and new aspects of antigen design to aid vaccine effectiveness.

摘要

新冠疫情大流行让我们学到了很多东西,其中最重要的一点是,疫苗是公共卫生的基石之一,有助于实现现代的长寿。虽然有几种不同的疫苗成功地阻止了各种传染病的发病率和死亡率,但许多病原体/疾病仍然难以通过有效的疫苗接种来解决。疫苗技术、免疫学、结构生物学和其他领域的最新进展可能会提供解决这些疾病的见解;它们也可能有助于提高社会为未来的大流行做好准备的能力。2022 年 6 月 1 日至 4 日,来自学术界、工业界和政府的疫苗学专家召开了基石研讨会“传染病疫苗开发的进展”,讨论了最先进的技术、疫苗介导免疫的最新进展以及辅助疫苗有效性的抗原设计的新方面。

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