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新冠疫情对德国儿童体检和疫苗接种的影响。

Effect of the COVID-19 Pandemic on Paediatric Check-Ups and Vaccinations in Germany.

作者信息

Lindinger Rudolf, Richter Hartmut, Reuter Thorsten Christian, Fischer Tim

机构信息

Medical Affairs Department, MSD Sharp & Dohme GmbH, 81673 Munich, Germany.

IQVIA Commercial GmbH & Co. OHG, 60549 Frankfurt, Germany.

出版信息

Vaccines (Basel). 2023 Mar 23;11(4):720. doi: 10.3390/vaccines11040720.

Abstract

Paediatric check-ups and vaccinations are provided and free of charge in Germany. Despite being hitherto generally well-received and adhered to, it is possible that the lockdown implemented due to the COVID-19 pandemic resulted in delays or even cancellations of critical paediatric visits with healthcare providers. This study attempts to quantify the rate and time to follow-up for check-ups in Germany using the retrospective IQVIA Disease Analyzer database. Additionally, timely administration of 4 vaccines (Hexavalent, pneumococcal, MMR-V, Rotavirus) was analysed to examine the impact of pandemic restrictions on vaccine uptake. The timeframes which were compared to determine the effects of COVID-19 were June 2018-December 2019 and March 2020-September 2021. The follow-up rates for paediatric check-ups were consistently lower in the COVID-19 phase, but generally ~90%. Follow-up rates for the vaccinations were distinctly higher during COVID-19. The time between events was almost unchanged for check-ups during the pandemic. For check-ups, age at initial event differed by less than a week between the phases. For vaccinations, the age differences were slightly higher, but exceeded one week in only two cases. The results show that the COVID-19 pandemic had little effect on paediatric check-ups and vaccinations in Germany.

摘要

在德国,儿童体检和疫苗接种是免费提供的。尽管迄今为止总体上受到广泛欢迎且人们普遍遵守,但由于新冠疫情实施的封锁措施可能导致与医疗服务提供者的关键儿童就诊延迟甚至取消。本研究试图利用回顾性艾昆纬疾病分析器数据库来量化德国儿童体检的随访率和随访时间。此外,还分析了4种疫苗(六联疫苗、肺炎球菌疫苗、MMR-V疫苗、轮状病毒疫苗)的及时接种情况,以研究疫情限制措施对疫苗接种率的影响。用于确定新冠疫情影响的时间框架为2018年6月至2019年12月以及2020年3月至2021年9月。在新冠疫情期间,儿童体检的随访率一直较低,但总体约为90%。在新冠疫情期间,疫苗接种的随访率明显更高。疫情期间体检的事件间隔时间几乎没有变化。对于体检,不同阶段首次体检时的年龄差异不到一周。对于疫苗接种,年龄差异略大,但只有两例超过一周。结果表明,新冠疫情对德国的儿童体检和疫苗接种影响不大。

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