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在 COVID-19 大流行期间,美国全生命周期疫苗接种趋势的变化:一项索赔数据库研究。

Changes in vaccine administration trends across the life-course during the COVID-19 pandemic in the United States: a claims database study.

机构信息

Center for Observational and Real-World Evidence (CORE), Merck & Co., Inc., Rahway, NJ, USA.

Medical Analytics Center, Merck & Co., Inc., Rahway, NJ, USA.

出版信息

Expert Rev Vaccines. 2023 Jan-Dec;22(1):481-494. doi: 10.1080/14760584.2023.2217257.

Abstract

BACKGROUND

This study provides an updated and expanded analysis of the impact of the COVID-19 pandemic on routine vaccinations across the life-course in the United States.

RESEARCH DESIGN AND METHODS

Routine wellness visits and vaccination rates were calculated using structured claims data for each month during the impact period (January 2020 to August 2022) and compared to the respective baseline period (January 2018 to December 2019). Monthly rates were aggregated as annual accumulated and cumulative percent changes.

RESULTS

The complete monthly rate interactive dataset can be viewed at https://vaccinationtrends.com. The greatest decrease in annual accumulated administration rates in the 0-2 and 4-6 years age groups was for the measles, mumps, and rubella vaccine; for adolescents and older adults, it was for human papillomavirus and pneumococcal vaccines, respectively. Routine in-person wellness visit rates recovered faster and more completely than vaccination rates in all age groups, indicating potential missed opportunities to administer vaccines during visits.

CONCLUSIONS

This updated analysis reveals that the negative impact of the COVID-19 pandemic on routine vaccination continued through 2021 and into 2022. Proactive efforts to reverse this decline are needed to increase individual- and population-level vaccination coverage and avoid the associated preventable morbidity, mortality, and health care costs.

摘要

背景

本研究对 2020 年 1 月至 2022 年 8 月期间(影响期)和相应的基线期(2018 年 1 月至 2019 年 12 月)美国全生命周期常规疫苗接种受 COVID-19 大流行影响的情况进行了更新和扩展分析。

研究设计与方法

使用结构化索赔数据,对每个月的常规健康访视和疫苗接种率进行计算,并与各自的基线期进行比较。每月的比率汇总为年度累积和累计百分比变化。

结果

完整的月度比率交互数据集可在 https://vaccinationtrends.com 查看。0-2 岁和 4-6 岁年龄组中,麻疹、腮腺炎和风疹疫苗的年度累积接种率降幅最大;青少年和老年人的人乳头瘤病毒和肺炎球菌疫苗接种率降幅最大。所有年龄组的常规门诊就诊率都比疫苗接种率更快、更全面地恢复,这表明在就诊期间可能错过了接种疫苗的机会。

结论

这项更新的分析表明,COVID-19 大流行对常规疫苗接种的负面影响持续到 2021 年,并延续到 2022 年。需要采取积极措施扭转这种下降趋势,以提高个人和人群的疫苗接种覆盖率,并避免相关的可预防发病率、死亡率和医疗保健费用。

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