Endocrine and Breast Surgery Unit, Department of General and Digestive Surgery, Instituto de Investigación, Hospital Universitario La Paz (IdiPAZ), Madrid, Spain.
Department of Medicine, Universidad de Alcalá, Madrid, Spain.
Langenbecks Arch Surg. 2023 May 29;408(1):213. doi: 10.1007/s00423-023-02959-5.
Thyroidectomy is one of the most commonly performed surgical procedures worldwide. Although the mortality rate is currently approaching 0%, the incidence of complications in such a frequent surgery is not insignificant. The most frequent are postoperative hypoparathyroidism, recurrent injury, and asphyxial hematoma. The size of the thyroid gland has traditionally been considered one of the most important risk factors, but there is currently no study that analyzes it independently. The objective of this study is to analyze whether the size of the thyroid gland is an isolated risk factor for the development of postoperative complications.
A prospective review of all patients who underwent total thyroidectomy at a third-level hospital between January 2019 and December 2021 was conducted. The thyroid volume was calculated preoperatively using ultrasound and, together with the weight of the definitive piece, was correlated with the development of postoperative complications.
One hundred twenty-one patients were included. When analyzing the incidence of complications based on the quartiles of weight and glandular volume, there were no significant differences in the incidence of transient or permanent hypoparathyroidism in any of the groups. No differences were found in terms of recurrent paralysis. No fewer parathyroid glands were visualized intraoperatively in patients with larger thyroid glands, nor did the number of them accidentally removed during surgery increase. In fact, a certain protective trend was observed with regard to the number of glands visualized and glandular size or in the relationship between thyroid volume and accidental gland removal, with no significant differences.
The size of the thyroid gland has not been shown to be a risk factor for the development of postoperative complications, contrary to what has traditionally been considered.
甲状腺切除术是全球最常见的手术之一。尽管目前死亡率接近 0%,但如此频繁的手术仍会出现不可忽视的并发症。最常见的是术后甲状旁腺功能减退症、再次损伤和窒息性血肿。甲状腺的大小传统上被认为是最重要的危险因素之一,但目前尚无研究对其进行独立分析。本研究旨在分析甲状腺的大小是否是术后并发症发生的一个独立危险因素。
对 2019 年 1 月至 2021 年 12 月在一家三级医院接受全甲状腺切除术的所有患者进行了前瞻性回顾。术前使用超声计算甲状腺体积,并与最终切除标本的重量一起,与术后并发症的发生相关联。
共纳入 121 例患者。根据重量和腺体体积的四分位值分析并发症的发生率,在任何一组中,永久性或暂时性甲状旁腺功能减退症的发生率均无显著差异。复发性麻痹也没有差异。在腺体较大的患者中,术中可见的甲状旁腺数量并没有减少,手术中意外切除的甲状旁腺数量也没有增加。实际上,在术中可见的腺体数量、腺体大小或甲状腺体积与意外腺体切除之间的关系方面,观察到了一定的保护趋势,但无显著差异。
与传统观点相反,甲状腺的大小并不是术后并发症发生的危险因素。