Institute of Databases and Information Systems, Ulm University, Ulm, Germany.
Institute of Clinical Epidemiology and Biometry, University of Würzburg, Würzburg, Germany.
Sci Rep. 2023 Jun 2;13(1):8989. doi: 10.1038/s41598-023-36172-7.
Mobile applications have gained popularity in healthcare in recent years. These applications are an increasingly important pillar of public health care, as they open up new possibilities for data collection and can lead to new insights into various diseases and disorders thanks to modern data analysis approaches. In this context, Ecological Momentary Assessment (EMA) is a commonly used research method that aims to assess phenomena with a focus on ecological validity and to help both the user and the researcher observe these phenomena over time. One phenomenon that benefits from this capability is the chronic condition tinnitus. TrackYourTinnitus (TYT) is an EMA-based mobile crowdsensing platform designed to provide more insight into tinnitus by repeatedly assessing various dimensions of tinnitus, including perception (i.e., perceived presence). Because the presence of tinnitus is the dimension that is of great importance to chronic tinnitus patients and changes over time in many tinnitus patients, we seek to predict the presence of tinnitus based on the not directly related dimensions of mood, stress level, arousal, and concentration level that are captured in TYT. In this work, we analyzed a dataset of 45,935 responses to a harmonized EMA questionnaire using different machine learning techniques. In addition, we considered five different subgroups after consultation with clinicians to further validate our results. Finally, we were able to predict the presence of tinnitus with an accuracy of up to 78% and an AUC of up to 85.7%.
近年来,移动应用在医疗保健领域越来越受欢迎。这些应用是公共医疗保健的一个日益重要的支柱,因为它们为数据收集开辟了新的可能性,并通过现代数据分析方法为各种疾病和障碍提供了新的见解。在这种情况下,生态瞬时评估(EMA)是一种常用的研究方法,旨在通过关注生态有效性来评估现象,并帮助用户和研究人员随着时间的推移观察这些现象。一种受益于这种能力的现象是慢性疾病耳鸣。TrackYourTinnitus(TYT)是一个基于 EMA 的移动众包平台,旨在通过反复评估耳鸣的各种维度,包括感知(即感知存在),从而更深入地了解耳鸣。由于耳鸣的存在是对慢性耳鸣患者非常重要的维度,并且在许多耳鸣患者中随时间变化,我们试图根据在 TYT 中捕获的与情绪、压力水平、觉醒和注意力水平等不直接相关的维度来预测耳鸣的存在。在这项工作中,我们使用不同的机器学习技术分析了一个包含 45935 个对协调后的 EMA 问卷的响应的数据集。此外,我们在与临床医生协商后考虑了五个不同的亚组,以进一步验证我们的结果。最终,我们能够以高达 78%的准确率和高达 85.7%的 AUC 预测耳鸣的存在。