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探索医护人员对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)疫苗犹豫的原因:一项横断面研究。

Explore the reasons for SARS-CoV-2 vaccine hesitancy among healthcare workers: a cross-sectional study.

作者信息

Bereda Gudisa

机构信息

Pharmacy, All Africa Leprosy, Tuberculosis and Rehabilitation Training Centre, Zenebework, Kolfe Keranio, Addis Ababa, Ethiopia.

出版信息

Ann Med Surg (Lond). 2023 Apr 14;85(6):2443-2450. doi: 10.1097/MS9.0000000000000628. eCollection 2023 Jun.

Abstract

UNLABELLED

Vaccine hesitancy is described by the WHO as "a delay in acceptance or refusal of safe immunizations notwithstanding the availability of vaccine services." In Ethiopia, the cumulative acceptance rate of the COVID-19 vaccination was 57.8%. Ethiopia had a lower rate of COVID-19 vaccination acceptance than was required to create herd immunity. This study was carried out to determine the prevalence of COVID-19 vaccine reluctance and its contributing factors. Based on the findings of the study, recommendations were made to the relevant bodies in order to reduce vaccine hesitancy and increase vaccination acceptability.

OBJECTIVES

A cross-sectional online-based study was conducted to better understand the reasons for SARS-CoV-2 vaccine hesitancy among healthcare workers (HCWs) in Oromia regional state, Ethiopia.

MATERIALS AND METHODS

A cross-sectional survey using an internet platform was conducted from 18 June 2021, to 29 June 2022. A multistage cluster sampling strategy was used to find participants, with each cluster representing a sampling unit made up of a set of population elements. Participants are then randomly chosen from those clusters. The data were entered in Epi Info 7.2.0.1, then exported to Microsoft Excel and imported into statistical programs for social sciences (26.0 version) for statistical analysis. Statistical significance was considered to be a value of less than 0.05.

RESULTS

Four hundred twenty-two HCWs completed the online survey. The majority of the HCWs were male (=234, 55.5%), urban residents (=396, 93.8%), protestants (=168, 39.8%), and married people (=232, 55.0%). The prevalence of HCWs reluctant to receive the SARS-CoV-2 vaccination was 69.7% (=294). Age from 19 to 34 [adjusted odds ratio (AOR) =1.48, 95% CI: 1.69-7.42, =<0.001], female sex (AOR =3.68, 95% CI =1.370-6.413, =0.002), income between 3501 and 8500 ETB (AOR =1.67, 95% CI =1.380-5.697, =0.048), information from websites (AOR =1.79, 95% CI =1.720-31.179, =0.013), vaccine skepticism (AOR =4.75, 95% CI =3.210-8.152, =0.009), and potential adverse effects of a SARS-CoV-2 vaccine (AOR =2.18, 95% CI =1.732-5.248, =0.043) were independent predictors of SARS-CoV-2 vaccine hesitancy among HCWs.

CONCLUSION AND RECOMMENDATIONS

HCWs were reluctant to get the SARS-CoV-2 immunization at a high percentage overall. To reduce hesitancy to receive the SARS-CoV-2 vaccination among HCWs, the Oromia regional state health bureau should be required to increase HCWs' knowledge of the COVID-19 vaccine by providing proper training for all HCWs.

摘要

未标注

世界卫生组织将疫苗犹豫描述为“尽管有疫苗服务,但在接受或拒绝安全免疫方面的延迟”。在埃塞俄比亚,新冠疫苗接种的累计接受率为57.8%。埃塞俄比亚的新冠疫苗接种接受率低于实现群体免疫所需的水平。开展这项研究是为了确定新冠疫苗犹豫的流行情况及其影响因素。根据研究结果,向相关机构提出了建议,以减少疫苗犹豫并提高疫苗接种的可接受性。

目的

开展一项基于网络的横断面研究,以更好地了解埃塞俄比亚奥罗米亚州医护人员对新冠病毒疫苗犹豫的原因。

材料与方法

于2021年6月18日至2022年6月29日使用互联网平台进行了一项横断面调查。采用多阶段整群抽样策略来寻找参与者,每个群代表一个由一组人群元素组成的抽样单位。然后从这些群中随机选择参与者。数据录入Epi Info 7.2.0.1,然后导出到Microsoft Excel并导入社会科学统计程序(26.0版)进行统计分析。统计学显著性被认为是P值小于0.05。

结果

422名医护人员完成了在线调查。大多数医护人员为男性(n = 234,55.5%)、城市居民(n = 396,93.8%)、新教徒(n = 168,39.8%)以及已婚人士(n = 232,55.0%)。不愿接种新冠病毒疫苗的医护人员比例为69.7%(n = 294)。19至34岁(调整优势比[AOR]=1.48,95%置信区间:1.69 - 7.42,P <= 0.001)、女性(AOR = 3.68,95%置信区间 = 1.370 - 6.413,P = 0.002)、收入在3501至8500埃塞俄比亚比尔之间(AOR = 1.67,95%置信区间 = 1.380 - 5.697,P = 0.048)、来自网站的信息(AOR = 1.79,95%置信区间 = 1.720 - 31.179,P = 0.013)、对疫苗的怀疑态度(AOR = 4.75,95%置信区间 = 3.210 - 8.152,P = 0.009)以及新冠病毒疫苗的潜在不良反应(AOR = 2.18, 95%置信区间 = 1.732 - 5.248, P = 0.043)是医护人员中新冠病毒疫苗犹豫的独立预测因素。

结论与建议

总体而言,医护人员中很大比例不愿接种新冠病毒疫苗。为减少医护人员对新冠病毒疫苗接种的犹豫,应要求奥罗米亚州卫生局通过为所有医护人员提供适当培训来增加他们对新冠疫苗的了解。

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