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HPV 血清学实验室牵头开展了一项标准化和协调人乳头瘤病毒血清学检测的倡议。

The HPV Serology Laboratory leads an initiative to standardize and harmonize human papillomavirus serology assays.

机构信息

HPV Serology Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.

出版信息

PLoS Pathog. 2023 Jun 29;19(6):e1011403. doi: 10.1371/journal.ppat.1011403. eCollection 2023 Jun.

Abstract

The HPV Serology Laboratory is leading a global partnership initiative aiming for standardization and harmonization of current serology assay platforms being used to assess immune responses to HPV vaccines. Serology standardization is particularly important given the increasing number of immunobridging trials relying on serology data for approval of new vaccine dosing schedules or vaccine formulations. The initiative was established in 2017 to enable comparisons of data between different vaccines and relevant studies as well as expedite the implementation of new vaccines and vaccine indications. The HPV Serology Laboratory has held or attended several meetings with partnering laboratories, including international meetings in 2017, 2018, and 2021.

摘要

HPV 血清学实验室正在牵头一个全球合作倡议,旨在标准化和协调当前用于评估 HPV 疫苗免疫反应的血清学检测平台。鉴于越来越多的免疫桥接试验依赖血清学数据来批准新的疫苗剂量方案或疫苗配方,因此血清学标准化尤为重要。该倡议成立于 2017 年,旨在实现不同疫苗和相关研究之间的数据比较,并加速新疫苗和疫苗适应证的实施。HPV 血清学实验室已与合作实验室举行或参加了多次会议,包括 2017 年、2018 年和 2021 年的国际会议。

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The second HPV serology meeting: Progress and challenges in standardization of human papillomavirus serology assays.
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