Institute for Health Metrics and Evaluation, University of Washington, Seattle.
Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston.
JAMA. 2023 Jul 3;330(1):52-61. doi: 10.1001/jama.2023.9043.
Evidence suggests that maternal mortality has been increasing in the US. Comprehensive estimates do not exist. Long-term trends in maternal mortality ratios (MMRs) for all states by racial and ethnic groups were estimated.
To quantify trends in MMRs (maternal deaths per 100 000 live births) by state for 5 mutually exclusive racial and ethnic groups using a bayesian extension of the generalized linear model network.
DESIGN, SETTING, AND PARTICIPANTS: Observational study using vital registration and census data from 1999 to 2019 in the US. Pregnant or recently pregnant individuals aged 10 to 54 years were included.
MMRs.
In 2019, MMRs in most states were higher among American Indian and Alaska Native and Black populations than among Asian, Native Hawaiian, or Other Pacific Islander; Hispanic; and White populations. Between 1999 and 2019, observed median state MMRs increased from 14.0 (IQR, 5.7-23.9) to 49.2 (IQR, 14.4-88.0) among the American Indian and Alaska Native population, 26.7 (IQR, 18.3-32.9) to 55.4 (IQR, 31.6-74.5) among the Black population, 9.6 (IQR, 5.7-12.6) to 20.9 (IQR, 12.1-32.8) among the Asian, Native Hawaiian, or Other Pacific Islander population, 9.6 (IQR, 6.9-11.6) to 19.1 (IQR, 11.6-24.9) among the Hispanic population, and 9.4 (IQR, 7.4-11.4) to 26.3 (IQR, 20.3-33.3) among the White population. In each year between 1999 and 2019, the Black population had the highest median state MMR. The American Indian and Alaska Native population had the largest increases in median state MMRs between 1999 and 2019. Since 1999, the median of state MMRs has increased for all racial and ethnic groups in the US and the American Indian and Alaska Native; Asian, Native Hawaiian, or Other Pacific Islander; and Black populations each observed their highest median state MMRs in 2019.
While maternal mortality remains unacceptably high among all racial and ethnic groups in the US, American Indian and Alaska Native and Black individuals are at increased risk, particularly in several states where these inequities had not been previously highlighted. Median state MMRs for the American Indian and Alaska Native and Asian, Native Hawaiian, or Other Pacific Islander populations continue to increase, even after the adoption of a pregnancy checkbox on death certificates. Median state MMR for the Black population remains the highest in the US. Comprehensive mortality surveillance for all states via vital registration identifies states and racial and ethnic groups with the greatest potential to improve maternal mortality. Maternal mortality persists as a source of worsening disparities in many US states and prevention efforts during this study period appear to have had a limited impact in addressing this health crisis.
有证据表明,美国的产妇死亡率一直在上升。目前还没有全面的估计数据。本研究旨在使用广义线性模型网络的贝叶斯扩展,估计所有州按种族和族裔划分的产妇死亡率(每 10 万活产儿的产妇死亡数)的长期趋势。
使用来自美国 1999 年至 2019 年的生命登记和人口普查数据,通过贝叶斯扩展的广义线性模型网络,对 5 个相互排斥的种族和族裔群体的州产妇死亡率(每 10 万活产儿的产妇死亡数)进行量化。
设计、地点和参与者:在美国进行的一项观察性研究,使用了 1999 年至 2019 年的生命登记和人口普查数据。纳入年龄在 10 至 54 岁之间的孕妇或近期孕妇。
产妇死亡率。
在 2019 年,大多数州的美洲印第安人和阿拉斯加原住民以及黑人的产妇死亡率高于亚洲、夏威夷原住民或其他太平洋岛民、西班牙裔和白人。在 1999 年至 2019 年期间,美洲印第安人和阿拉斯加原住民的州观察中位数死亡率从 14.0(IQR,5.7-23.9)增加到 49.2(IQR,14.4-88.0),黑人的死亡率从 26.7(IQR,18.3-32.9)增加到 55.4(IQR,31.6-74.5),亚洲、夏威夷原住民或其他太平洋岛民的死亡率从 9.6(IQR,5.7-12.6)增加到 20.9(IQR,12.1-32.8),西班牙裔的死亡率从 9.6(IQR,6.9-11.6)增加到 19.1(IQR,11.6-24.9),白种人的死亡率从 9.4(IQR,7.4-11.4)增加到 26.3(IQR,20.3-33.3)。在 1999 年至 2019 年的每一年中,黑人的死亡率最高。1999 年至 2019 年期间,美洲印第安人和阿拉斯加原住民的州中位数死亡率增幅最大。自 1999 年以来,美国所有种族和族裔群体以及美洲印第安人和阿拉斯加原住民、亚洲、夏威夷原住民或其他太平洋岛民和黑人群体的州死亡率中位数都有所增加,而美洲印第安人和阿拉斯加原住民以及黑人群体的州死亡率中位数在 2019 年达到最高。
虽然美国所有种族和族裔群体的产妇死亡率仍然高得令人无法接受,但美洲印第安人和阿拉斯加原住民以及黑人面临更高的风险,特别是在几个此前没有突出这些不平等现象的州。美洲印第安人和阿拉斯加原住民和亚洲、夏威夷原住民或其他太平洋岛民的州死亡率中位数仍在继续增加,即使在死亡证明上增加了妊娠复选框之后也是如此。黑人的州死亡率中位数仍然是美国最高的。通过生命登记对所有州进行全面的死亡率监测,可以确定有最大潜力改善产妇死亡率的州和种族群体。产妇死亡率仍然是美国许多州恶化的不平等现象的一个来源,在此研究期间,预防工作似乎对解决这一卫生危机没有产生多大影响。