Verras Georgios-Ioannis, Mulita Francesk, Pouwels Sjaak, Parmar Chetan, Drakos Nikolas, Bouchagier Konstantinos, Kaplanis Charalampos, Skroubis George
Department of Surgery, General University Hospital of Patras, 26504 Patras, Greece.
Department of General, Abdominal and Minimally Invasive Surgery, Helios Klinikum, 47805 Krefeld, Germany.
J Clin Med. 2023 Jul 28;12(15):4973. doi: 10.3390/jcm12154973.
Morbid obesity is a well-defined chronic disease, the incidence of which is constantly rising. Surgical treatment of morbid obesity has produced superior outcomes compared to conventional weight loss measures. Currently, there is a gap in the literature regarding long-term outcomes. Our single-institution, retrospective cohort study aims to evaluate weight loss outcomes, comorbidity reduction, and adverse effects at 10 years following Roux-en-Y Gastric Bypass (RYGB), Biliopancreatic Diversion (BPD), and Sleeve Gastrectomy (SG).
We included all consecutive patients with 10-year follow-up records operated on within our institution. The comparison was carried out on the average percentage of weight and BMI loss. Nausea and vomiting were evaluated through self-reporting Likert scales. Diabetes resolution and nutritional deficiencies were also evaluated.
A total of 490 patients from 1995 up to 2011 were included in our study. Of these, 322 underwent RYGB, 58 underwent long-limb BPD, 34 underwent laparoscopic RYGB with fundus excision, 47 underwent laparoscopic SG, and 29 underwent laparoscopic RYGB as a revision of prior SG. RYGB and BPD were significantly associated with higher percentages of weight loss (37.6% and 37.5%), but were not found to be independent predictors of weight loss. Nausea and vomiting were associated with SG and laparoscopic RYGB with fundus excision, more so than the other operations. No differences were observed regarding diabetes resolution and nutritional deficiencies.
Longer follow-up reports are important for the comparison of outcomes between different types of bariatric operations. BPD and RYGB resulted in superior weight loss, with no observed differences in diabetes resolution and adverse outcomes.
病态肥胖是一种明确的慢性疾病,其发病率持续上升。与传统的减肥措施相比,病态肥胖的外科治疗产生了更好的效果。目前,关于长期结果的文献存在空白。我们的单机构回顾性队列研究旨在评估胃旁路术(RYGB)、胆胰转流术(BPD)和袖状胃切除术(SG)术后10年的体重减轻结果、合并症减少情况及不良反应。
我们纳入了在本机构接受手术且有10年随访记录的所有连续患者。对体重和BMI减轻的平均百分比进行比较。通过自我报告的李克特量表评估恶心和呕吐情况。还评估了糖尿病缓解情况和营养缺乏情况。
我们的研究纳入了1995年至2011年的490例患者。其中,322例行RYGB,58例行长肢BPD,34例行带胃底切除术的腹腔镜RYGB,47例行腹腔镜SG,29例行腹腔镜RYGB作为先前SG的修正手术。RYGB和BPD与更高的体重减轻百分比显著相关(分别为37.6%和37.5%),但未被发现是体重减轻的独立预测因素。恶心和呕吐与SG及带胃底切除术的腹腔镜RYGB相关,比其他手术更明显。在糖尿病缓解和营养缺乏方面未观察到差异。
更长时间的随访报告对于比较不同类型减肥手术的结果很重要。BPD和RYGB导致了更好的体重减轻,在糖尿病缓解和不良结果方面未观察到差异。