新冠疫苗接种情况、安全性及态度：一项针对普通公众第一剂和第二剂接种情况的横断面研究

Uptake, Safety and Attitudes Towards COVID-19 Vaccination: A Cross-Sectional Study on First and Second Doses Among the General Public.

作者信息

Mahmoud Mansour A, Ibrahim Alnada, Alharbi Fawaz, Alalawi Ali Mohammed, Alnezary Faris, Aldafiri Ahmed, Alahmadi Yaser, Alolayan Sultan Othman, Althaqfan Sultan S, Alsultan Mohammed M, Omer Safaa, Alsahly Musaad B

机构信息

Department of Clinical and Hospital Pharmacy, College of Pharmacy, Taibah University, Al-Madinah Al-Munawarah, Saudi Arabia.

Department of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O.Box 84428, Riyadh, 11671, Saudi Arabia.

出版信息

Risk Manag Healthc Policy. 2023 Aug 18;16:1633-1643. doi: 10.2147/RMHP.S418300. eCollection 2023.

DOI:10.2147/RMHP.S418300

PMID:37614963

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10443679/

Abstract

OBJECTIVE

To investigate public uptake, attitudes and the safety of the first and second doses of COVID-19 vaccination.

METHODS

This was a cross-sectional web-based survey study. A self-administered questionnaire was prepared from a literature search and information about COVID-19 available at various resources. The developed questionnaire was validated for readability by experts and refined in light of the feedback received from the experts and the final version was prepared. The reliability of the questionnaire was 0.7 which shows an acceptable level of scale internal consistency. The data analysis was performed using IBM SPSS software (version 25).

RESULTS

A total of 513 participants completed the survey, including 311 (60.6%) women and 202 (39.4%) men. The mean age was (31.5±12.8) years. It was found that 493 (96.1%) took the first and second doses of COVID-19 and 376 (73.3%) suffered from side effects, of these 14% (56/376) reported the side effects to the health authorities. The most common side effects were fatigue (51.5%), fever (42.3%), headache (39.5%), and injection site pain (37.6%). Half of the participants (50.5%) had a positive attitude towards COVID-19 preventive measures. Females had higher odds of experiencing side effects than males OR (95% CI); 2.002 (1.312-3.056). Individuals living in urban areas had lower odds of experiencing side effects than those living in rural areas OR (95% CI); 0.364 (0.142-0.933).

CONCLUSION

Vaccine uptake was massive and side effects due to the COVID-19 vaccine were common but minor. The majority of the participants had positive attitudes towards recommended COVID-19 preventive measures. Being female and living in rural areas were associated with experiencing side effects.

摘要

目的

调查新冠病毒疫苗第一剂和第二剂的公众接种情况、态度及安全性。

方法

这是一项基于网络的横断面调查研究。通过文献检索以及从各种资源获取的有关新冠病毒的信息，编制了一份自填式问卷。所编制的问卷经专家验证其可读性，并根据专家反馈进行完善，最终形成定稿。问卷的信度为0.7，表明量表内部一致性水平可接受。使用IBM SPSS软件（版本25）进行数据分析。

结果

共有513名参与者完成了调查，其中女性311名（60.6%），男性202名（39.4%）。平均年龄为（31.5±12.8）岁。结果发现，493名（96.1%）接种了新冠病毒疫苗的第一剂和第二剂，376名（73.3%）出现了副作用，其中14%（56/376）向卫生当局报告了副作用。最常见的副作用是疲劳（51.5%）、发热（42.3%）、头痛（39.5%）和注射部位疼痛（37.6%）。一半的参与者（50.5%）对新冠病毒预防措施持积极态度。女性出现副作用的几率高于男性，比值比（95%可信区间）为2.002（1.312 - 3.056）。居住在城市地区的个体出现副作用的几率低于居住在农村地区的个体，比值比（95%可信区间）为0.364（0.142 - 0.933）。