Alwithanani Naif
Department of Oral and Maxillofacial Surgery and Diagnostic Science, Taif University, Taif, Saudi Arabia.
J Pharm Bioallied Sci. 2023 Jul;15(Suppl 1):S64-S71. doi: 10.4103/jpbs.jpbs_516_22. Epub 2023 Jul 5.
Tobacco has been linked multiple times to many health implications. The relationship between periodontitis and tobacco was thoroughly investigated in this systemic review to evaluate if tobacco specifically smoking impacts the progression of periodontal through impairing vascular and immunity mediators processes.
The manual and electronic literature searches up to 2020 in the databanks of the EMBASE, MEDLINE, PUBMED, and SCOPUS were conducted. The search terms were "periodontitis," "periodontitis diseases," "smoking," "tobacco use," "tobacco," and "cigarette, pipe, and cigar." The types of studies included were restricted to the original studies and human trials. Analyses of subgroups and meta-regression were used to calculate the heterogeneity.
15 papers total were considered in the review, however only 14 of them provided information that could be used in the meta-analysis. Smoking raises the incidence of periodontitis by 85% according to pooled adjusted risk ratios (risk ratio 1.845, CI (95%) =1.5, 2.2). The results of a meta-regression analysis showed that age, follow-up intervals, periodontal disease, the severity of periodontitis, criteria used to determine periodontal status, and loss to follow-up accounted for 54.2%, 10.7%, 13.5%, and 2.1% of the variation in study results.
Smoking has an undesirable impact on periodontal incidence and development. Therefore, when taking the history of the patients at the initial visits the information about the habit of smoking has to be thoroughly noted.
烟草多次与多种健康问题相关联。本系统评价对牙周炎与烟草之间的关系进行了全面调查,以评估烟草(特别是吸烟)是否通过损害血管和免疫介质过程影响牙周炎的进展。
在EMBASE、MEDLINE、PUBMED和SCOPUS数据库中进行了截至2020年的手动和电子文献检索。检索词为“牙周炎”、“牙周疾病”、“吸烟”、“烟草使用”、“烟草”以及“香烟、烟斗和雪茄”。纳入的研究类型仅限于原始研究和人体试验。采用亚组分析和meta回归分析来计算异质性。
该评价共纳入15篇论文,但其中只有14篇提供了可用于meta分析的信息。根据合并调整风险比,吸烟使牙周炎发病率提高85%(风险比1.845,95%置信区间=1.5,2.2)。meta回归分析结果显示,年龄、随访间隔、牙周疾病、牙周炎严重程度、确定牙周状况所用标准以及失访在研究结果变异中所占比例分别为54.2%、10.7%、13.5%和2.1%。
吸烟对牙周炎的发病率和发展有不良影响。因此,在初次就诊询问患者病史时,必须详细记录吸烟习惯相关信息。