Suppr超能文献

维持性血液透析的慢性肾脏病患者糖尿病酮症酸中毒的管理:一例报告

Management of Diabetic Ketoacidosis in a Patient With Chronic Kidney Disease Under Maintenance Hemodialysis: A Case Report.

作者信息

Regmi Milan, Karki Anurag, Bhandari Sanjeev, Shrestha Moon, Kafle Pooja

机构信息

Internal Medicine, Tribhuvan University Institute of Medicine, Kathmandu, NPL.

Critical Care Medicine, Tribhuvan University Institute of Medicine, Kathmandu, NPL.

出版信息

Cureus. 2023 Jul 30;15(7):e42700. doi: 10.7759/cureus.42700. eCollection 2023 Jul.

Abstract

Diabetic ketoacidosis (DKA) is a potentially fatal metabolic complication seen in individuals with type 1 diabetes mellitus (DM) or type 2 DM under stress, such as infections and non-compliance with treatment. DKA in chronic kidney disease (CKD) patients undergoing maintenance hemodialysis (HD) presents challenges due to the unique pathophysiology and the absence of specific management guidelines. This case report highlights the importance of tailoring the treatment of DKA based on the specific requirements of CKD patients on HD. The presented case involves a 47-year-old female with type 2 DM and CKD who developed DKA in the context of a urinary tract infection (UTI). Management included insulin infusion, cautious fluid replacement therapy, electrolyte monitoring, and identifying precipitating factors, such as an infection. The case highlights the complexity of DKA management in CKD patients and the necessity of individualized approaches. More studies and guidelines are needed to optimize the proper management of DKA in CKD patients.

摘要

糖尿病酮症酸中毒(DKA)是1型糖尿病(DM)患者或应激状态下的2型糖尿病患者(如感染和治疗依从性差)中可能发生的致命性代谢并发症。接受维持性血液透析(HD)的慢性肾脏病(CKD)患者发生DKA,因其独特的病理生理学和缺乏具体的管理指南而面临挑战。本病例报告强调了根据接受HD的CKD患者的具体需求调整DKA治疗的重要性。所呈现的病例是一名47岁患有2型糖尿病和CKD的女性,在尿路感染(UTI)的情况下发生了DKA。治疗措施包括胰岛素输注、谨慎的补液治疗、电解质监测以及识别诱发因素,如感染。该病例突出了CKD患者DKA管理的复杂性以及个体化方法的必要性。需要更多的研究和指南来优化CKD患者DKA的恰当管理。

相似文献

1
Management of Diabetic Ketoacidosis in a Patient With Chronic Kidney Disease Under Maintenance Hemodialysis: A Case Report.
Cureus. 2023 Jul 30;15(7):e42700. doi: 10.7759/cureus.42700. eCollection 2023 Jul.
2
Diabetic ketoacidosis: risk factors and management strategies.
Treat Endocrinol. 2003;2(2):95-108. doi: 10.2165/00024677-200302020-00003.
3
Challenges in management of diabetic ketoacidosis in hemodialysis patients, case presentation and review of literature.
Diabetes Metab Syndr. 2019 Jul-Aug;13(4):2481-2487. doi: 10.1016/j.dsx.2019.06.022. Epub 2019 Jun 28.
4
Management of Diabetic Ketoacidosis in Adults: A Narrative Review.
Saudi J Med Med Sci. 2020 Sep-Dec;8(3):165-173. doi: 10.4103/sjmms.sjmms_478_19. Epub 2020 Aug 20.
5
Management of diabetic ketoacidosis in special populations.
Diabetes Res Clin Pract. 2021 Apr;174:108744. doi: 10.1016/j.diabres.2021.108744. Epub 2021 Mar 10.
6
Nephrogenic diabetes insipidus with new onset diabetic ketoacidosis in a child - challenges in fluid and electrolyte management.
Pediatr Nephrol. 2022 Sep;37(9):2209-2212. doi: 10.1007/s00467-022-05436-1. Epub 2022 Mar 14.
7
Diabetic Ketoacidosis: Clinical Characteristics and Precipitating Factors.
Cureus. 2020 Oct 4;12(10):e10792. doi: 10.7759/cureus.10792.
8
Acute mountain sickness induced diabetic ketoacidosis managed with hemodialysis: A case report.
Ann Med Surg (Lond). 2020 Jun 13;56:165-168. doi: 10.1016/j.amsu.2020.06.012. eCollection 2020 Aug.
10
Diabetic Ketoacidosis in Patients with Type 2 Diabetes on Sodium-Glucose Cotransporter-2 Inhibitors - A Case Series.
Rev Recent Clin Trials. 2018;13(2):156-160. doi: 10.2174/1574887113666180314101436.

引用本文的文献

1
The effect of renal function on the clinical outcomes and management of patients hospitalized with hyperglycemic crises.
Front Endocrinol (Lausanne). 2025 Jan 9;15:1445040. doi: 10.3389/fendo.2024.1445040. eCollection 2024.

本文引用的文献

2
Challenges in management of diabetic ketoacidosis in hemodialysis patients, case presentation and review of literature.
Diabetes Metab Syndr. 2019 Jul-Aug;13(4):2481-2487. doi: 10.1016/j.dsx.2019.06.022. Epub 2019 Jun 28.
3
Guidelines and controversies in the management of diabetic ketoacidosis - A mini-review.
World J Diabetes. 2018 Dec 15;9(12):226-229. doi: 10.4239/wjd.v9.i12.226.
5
Lesson of the month 1: Diabetic ketoacidosis in established renal failure.
Clin Med (Lond). 2016 Aug;16(4):392-3. doi: 10.7861/clinmedicine.16-4-392.
6
Comparison of diabetic ketoacidosis in patients with type-1 and type-2 diabetes mellitus.
Am J Med Sci. 2013 Apr;345(4):326-330. doi: 10.1097/MAJ.0b013e31827424ab.
7
Diabetic ketoacidosis: a current appraisal of pathophysiology and management.
Clin Pediatr (Phila). 2009 Mar;48(2):135-44. doi: 10.1177/0009922808323907. Epub 2008 Nov 20.
8
Ketoacidosis occurs in both Type 1 and Type 2 diabetes--a population-based study from Northern Sweden.
Diabet Med. 2008 Jul;25(7):867-70. doi: 10.1111/j.1464-5491.2008.02461.x.
9
Diabetic ketoacidosis in Peruvian patients with type 2 diabetes mellitus.
Endocr Pract. 2008 May-Jun;14(4):442-6. doi: 10.4158/EP.14.4.442.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验