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琼脂糖凝胶:真皮填充剂概述及700例患者的临床经验

Agarose Gel: An Overview of the Dermal Filler and a Clinical Experience With 700 Patients.

作者信息

Buhsem Omer, Kirazoglu Ahmet

出版信息

Aesthet Surg J Open Forum. 2023 Jun 14;5:ojad051. doi: 10.1093/asjof/ojad051. eCollection 2023.

Abstract

BACKGROUND

Dermal fillers currently in the market have several advantages and disadvantages over each other. Agarose gel (AG) is a unique material due to its special rheological characteristics and gel-forming capability.

OBJECTIVES

The authors aimed to share their clinical experience on AG for a variety of facial augmentation procedures and its long-term results.

METHODS

The study population consisted of 700 patients (532 females; 168 males) aged 18 to 52 years. Follow-up visits were at 1, 3, 6, 12, and 24 months after the injections. Patient satisfaction was evaluated on a scale from 0 to 10 using a survey and clinical improvement was evaluated using the Global Aesthetic Improvement Scale (GAIS) by 2 independent plastic surgeons before the injection and at 1-year follow-up.

RESULTS

Eighty-two percent of the patients scored 1 or 2 (exceptional or great improvement) on GAIS. Eighty-five percent of the patients scored 8 or above (very satisfied). Most patients experienced at least 80% persistence of effect at 1-year follow-up.

CONCLUSIONS

AG appears to be suitable for a variety of facial augmentation and contouring applications, as it is safe and has long-lasting favorable cosmetic efficacy.

摘要

背景

目前市场上的真皮填充剂各有优缺点。琼脂糖凝胶(AG)因其特殊的流变学特性和凝胶形成能力而成为一种独特的材料。

目的

作者旨在分享他们在多种面部填充手术中使用AG的临床经验及其长期效果。

方法

研究人群包括700名年龄在18至52岁之间的患者(532名女性;168名男性)。在注射后1、3、6、12和24个月进行随访。通过调查使用0至10分的量表评估患者满意度,并由2名独立的整形外科医生在注射前和1年随访时使用全球美学改善量表(GAIS)评估临床改善情况。

结果

82%的患者在GAIS上得分为1或2分(显著改善或极大改善)。85%的患者得分8分及以上(非常满意)。大多数患者在1年随访时效果持续至少80%。

结论

AG似乎适用于多种面部填充和轮廓塑造应用,因为它安全且具有持久良好的美容效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b96a/10494782/8a0ce73947a6/ojad051f1.jpg

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