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肥胖症的流行先于社会被认为的致肥胖因子的转变而出现。

Emergence of the obesity epidemic preceding the presumed obesogenic transformation of the society.

机构信息

Section of Biostatistics, Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

H. Lundbeck A/S, Copenhagen, Denmark.

出版信息

Sci Adv. 2023 Sep 15;9(37):eadg6237. doi: 10.1126/sciadv.adg6237. Epub 2023 Sep 13.

Abstract

The obesity epidemic, evolving in many countries since the 1970s, has been attributed to the widespread contemporary so-called obesogenic transformation of the societies, but what preceded the epidemic? Using quantile regression, we studied the trends by year of birth in the percentile distribution of body mass index (BMI = weight/height) of 320,962 Danish school children, born from 1930 to 1976, and of 205,153 Danish young conscripts, born from 1939 to 1959. The overall trend of the percentiles of the BMI distributions were found to be linear across the years of birth. While the percentiles below the 75th were almost stable, those above showed a steadily steeper rise the more extreme the percentile among both school children and young men is. These changes, indicating the emergence of the obesity epidemic, preceded the presumed obesogenic transformation of the society by several decades and imply that other, so far unknown, factors have been involved.

摘要

自 20 世纪 70 年代以来,许多国家都出现了肥胖症流行的情况,这被归因于当前社会所谓的致肥胖环境的广泛转变,但在此之前又发生了什么呢?我们使用分位数回归研究了丹麦 320962 名小学生(1930 年至 1976 年出生)和 205153 名丹麦年轻应征者(1939 年至 1959 年出生)的出生年份与体重指数(BMI=体重/身高)百分位数分布的趋势。我们发现,BMI 分布的百分位数总体趋势呈线性变化。虽然低于第 75 百分位的百分位数几乎保持稳定,但在小学生和年轻男性中,高于第 75 百分位的百分位数的上升趋势则更为陡峭,而且其极端程度也越来越高。这些变化表明肥胖症的出现早于社会所谓的致肥胖环境的转变几十年,这意味着涉及到其他目前尚不清楚的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78b9/10499309/c4446a5742bd/sciadv.adg6237-f1.jpg

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