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全髋关节置换术与半髋关节置换术治疗 75 岁以上活动型老年股骨颈骨折移位患者的回顾性研究。

Total hip arthroplasty versus hemiarthroplasty in the treatment of active elderly patients over 75 years with displaced femoral neck fractures: a retrospective study.

机构信息

The First Affiliated Hospital of Guangxi University of Science and Technology, Guangxi University of Science and Technology, 124 Yuejin Road, Liuzhou, 545001, Guangxi Province, China.

出版信息

BMC Musculoskelet Disord. 2023 Sep 20;24(1):745. doi: 10.1186/s12891-023-06860-6.

Abstract

BACKGROUND

Femoral neck fractures are associated with substantial morbidity and mortality for older adults. Total hip arthroplasty (THA) and hemiarthroplasty (HA) are widely used in elderly patients with displaced femoral neck fractures (DFNF), but there is still controversy refering to the optimal chose for the management of DFNF in active elderly patients.

METHODS

This is a retrospective cohort study that incorporates medical record review with an outcomes management database. 73 patients who underwent HA and 66 patients who underwent THA were identified from January 2015 to December 2017. Data of age, gender, BMI, comorbidity status, operation time, blood loss, hospitalization time, in-hospital complication were collected and analyzed. Clinical follow-up and radiographic examinations were performed at approximately five years, and hip complications, Harris Hip Score (HHS) and EuroQol-5 Dimensions (EQ-5D) were assessed.

RESULTS

Preoperative general data of sex, age, BMI and charlson comorbidity score of THA group(n=55) has no statistically significant difference with that of HA group. Patients treated by THA had significantly longer operation time (105.5 vs 76.7 minutes; P < 0.001), more blood loss (524.1 vs 350.1 ml; P < 0.001) and longer hospitalization time (15.8 vs 13.8 days; P < 0.001). There was no significant differences between two groups in complications (32.7% vs 25.8%, P=0.432). No patients died during the hospitalization. After five years, only 33 patients in the THA group and 34 patents in the HA group were still alive, and the fraction surviving were not statistically significant between two groups (60.0% vs 54.8%, P> 0.05). The differences in hip function in favor of THA appeared to increase after the five-year follow-up, and the difference was significant in terms of the total Harris hip score (81.3 vs 73.1, P < 0.001) as well as in the dimensions of pain (38.9 vs 35.9, P=0.033), function (33.7 vs 29.2, P=0.001), absence of deformity (4.0 vs 3.9, P=0.023) and range of motion (4.6 vs 4.2, P=0.008). There was no significant differences between groups in hip dislocation rate (6.1% vs 0.0%, P=0.239). The erosion rate of hip joint in the THA group was significantly lower than that of the HA group (0.0% vs 26.5%, P=0.002). The health-related quality of life, according to EQ-5D index score, was found to be higher (0.69 vs 0.63, P= 0.001) in the THA group than the HA group after five years.

CONCLUSION

THA may be a preferred management option for active elderly patients over 75 years. The more extensive surgery of THA is not associated with higher in-hospital complication rate or mortality rate. These patients can benefit from THA in terms of hip function and quality of life.

TRIAL REGISTRATION

No.

摘要

背景

股骨颈骨折会给老年人带来很大的发病率和死亡率。全髋关节置换术(THA)和人工股骨头置换术(HA)广泛应用于移位型股骨颈骨折(DFNF)的老年患者,但对于活动能力较强的老年患者,DFNF 的最佳治疗方案仍存在争议。

方法

这是一项回顾性队列研究,结合了病历回顾和结果管理数据库。我们从 2015 年 1 月至 2017 年 12 月期间确定了 73 例接受 HA 和 66 例接受 THA 的患者。收集并分析了年龄、性别、BMI、合并症状态、手术时间、失血量、住院时间、院内并发症等数据。大约在五年后进行临床随访和影像学检查,并评估髋关节并发症、Harris 髋关节评分(HHS)和欧洲五维健康量表(EQ-5D)。

结果

THA 组(n=55)术前一般数据中的性别、年龄、BMI 和 Charlson 合并症评分与 HA 组无统计学差异。THA 组的手术时间(105.5 分钟比 76.7 分钟;P<0.001)、失血量(524.1 毫升比 350.1 毫升;P<0.001)和住院时间(15.8 天比 13.8 天;P<0.001)明显更长。两组并发症发生率(32.7%比 25.8%;P=0.432)无统计学差异。住院期间无患者死亡。五年后,THA 组仅有 33 例和 HA 组仅有 34 例患者仍存活,两组的存活率无统计学差异(60.0%比 54.8%;P>0.05)。THA 组的髋关节功能优势似乎在五年随访后增加,在总 Harris 髋关节评分(81.3 比 73.1;P<0.001)以及疼痛维度(38.9 比 35.9;P=0.033)、功能维度(33.7 比 29.2;P=0.001)、无畸形维度(4.0 比 3.9;P=0.023)和活动范围维度(4.6 比 4.2;P=0.008)方面均具有显著优势。两组髋关节脱位率(6.1%比 0.0%;P=0.239)无统计学差异。THA 组髋关节侵蚀率明显低于 HA 组(0.0%比 26.5%;P=0.002)。THA 组的健康相关生活质量,根据 EQ-5D 指数评分,五年后明显高于 HA 组(0.69 比 0.63;P=0.001)。

结论

THA 可能是 75 岁以上活动能力较强的老年患者的首选治疗方案。THA 更广泛的手术并不与更高的院内并发症发生率或死亡率相关。这些患者在髋关节功能和生活质量方面可以从 THA 中获益。

试验注册

无。

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