基于伤口内部微环境的天然高分子材料对皮肤愈合的影响：综述
Effect of natural polymer materials on skin healing based on internal wound microenvironment: a review.
作者信息
Yang Ying, Li Bingbing, Wang Mengxin, Pan Shicong, Wang Yu, Gu Jinhui
机构信息
The People's Hospital of SND, Suzhou, Jiangsu, China.
Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
出版信息
Front Chem. 2023 Sep 5;11:1257915. doi: 10.3389/fchem.2023.1257915. eCollection 2023.
The concept of wound microenvironment has been discussed for a long time. However, the mechanism of the internal microenvironment is relatively little studied. Here, we present a systematic discussion on the mechanism of natural polymer materials such as chitosan, cellulose, collagen and hyaluronic acid through their effects on the internal wound microenvironment and regulation of wound healing, in order to more comprehensively explain the concept of wound microenvironment and provide a reference for further innovative clinical for the preparation and application of wound healing agents.
伤口微环境的概念已经讨论了很长时间。然而，内部微环境的机制研究相对较少。在此，我们通过壳聚糖、纤维素、胶原蛋白和透明质酸等天然高分子材料对伤口内部微环境的影响及其对伤口愈合的调控，对其机制进行系统的探讨，以便更全面地阐释伤口微环境的概念，并为伤口愈合剂的制备和应用的进一步临床创新提供参考。
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