朝着一种强效且快速可逆的右美托咪定为基础的全身麻醉剂努力。
Towards a potent and rapidly reversible Dexmedetomidine-based general anesthetic.
机构信息
Department of Anesthesia and Critical Care, The University of Chicago, Chicago, IL, United States of America.
Department of Neurobiology, Pharmacology and Physiology, The University of Chicago, Chicago, IL, United States of America.
出版信息
PLoS One. 2023 Sep 26;18(9):e0291827. doi: 10.1371/journal.pone.0291827. eCollection 2023.
Abstract
Our results suggest that Dex supplemented with a low dose of a second agent creates a potent anesthetic that is rapidly reversed by atipamezole and caffeine.
摘要
我们的结果表明，DEX 与低剂量的第二种药物联合使用会产生一种强效的麻醉剂，这种麻醉剂可以被阿替美唑和咖啡因迅速逆转。
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