脑 PET 仪器的新视野。
New Horizons in Brain PET Instrumentation.
机构信息
Department of Radiology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital; Department of Physics, Massachusetts Institute of Technology.
Department of Radiology, A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital; Harvard Medical School.
出版信息
PET Clin. 2024 Jan;19(1):25-36. doi: 10.1016/j.cpet.2023.08.001. Epub 2023 Oct 6.
Abstract
Dedicated brain PET scanners are optimized to provide high sensitivity and high spatial resolution compared with existing whole-body PET systems, and they can be much cheaper to produce and install in various clinical and research settings. Advancements in detector technology over the past few years have placed several standalone PET, PET/computed tomography, and PET/MR systems on or near the commercial market; the features and capabilities of these systems will be reviewed here.
摘要
专用脑部 PET 扫描仪经过优化，与现有的全身 PET 系统相比，具有更高的灵敏度和更高的空间分辨率，并且在各种临床和研究环境中生产和安装的成本也低得多。过去几年中，探测器技术的进步使数台独立的 PET、PET/CT 和 PET/MR 系统进入或接近商业市场；这里将对这些系统的特点和功能进行综述。
相似文献
1
New Horizons in Brain PET Instrumentation.
PET Clin. 2024 Jan;19(1):25-36. doi: 10.1016/j.cpet.2023.08.001. Epub 2023 Oct 6.
2
Development of Dedicated Brain PET Imaging Devices: Recent Advances and Future Perspectives.
J Nucl Med. 2019 Aug;60(8):1044-1052. doi: 10.2967/jnumed.118.217901. Epub 2019 Apr 26.
3
Development and performance of SIAT bPET: a high-resolution and high-sensitivity MR-compatible brain PET scanner using dual-ended readout detectors.
Eur J Nucl Med Mol Imaging. 2024 Jan;51(2):346-357. doi: 10.1007/s00259-023-06458-z. Epub 2023 Oct 2.
4
High-resolution and high-sensitivity PET for quantitative molecular imaging of the monoaminergic nuclei: A GATE simulation study.
Med Phys. 2022 Jul;49(7):4430-4444. doi: 10.1002/mp.15653. Epub 2022 May 15.
5
Whole-body magnetic resonance imaging and positron emission tomography-computed tomography in oncology.
Top Magn Reson Imaging. 2007 Jun;18(3):193-202. doi: 10.1097/RMR.0b013e318093e6bo.
6
First prototyping of a dedicated PET system with the hemisphere detector arrangement.
Phys Med Biol. 2019 Mar 8;64(6):065004. doi: 10.1088/1361-6560/ab012c.
7
Study of compatibility between a 3T MR system and detector modules for a second-generation RF-penetrable TOF-PET insert for simultaneous PET/MRI.
Med Phys. 2023 Jun;50(6):3389-3400. doi: 10.1002/mp.16354. Epub 2023 Apr 7.
8
Comparison of dedicated breast positron emission tomography and whole-body positron emission tomography/computed tomography images: a common phantom study.
Ann Nucl Med. 2020 Feb;34(2):119-127. doi: 10.1007/s12149-019-01422-0. Epub 2019 Nov 25.
9
Count rate performance of brain-dedicated PET scanners: a Monte Carlo simulation study.
Phys Med Biol. 2019 Oct 31;64(21):215013. doi: 10.1088/1361-6560/ab452f.
10
Positron emission tomography instrumentation.
Radiol Clin North Am. 2001 Sep;39(5):919-29. doi: 10.1016/s0033-8389(05)70320-1.
引用本文的文献
1
Consistency Analysis of Centiloid Values Across Three Commercial Software Platforms for Amyloid PET Quantification.
Diagnostics (Basel). 2025 Jun 24;15(13):1599. doi: 10.3390/diagnostics15131599.
2
A new design to improve time resolution in a time of flight brain PET using dual layer offset scintillator crystals.
Sci Rep. 2025 May 5;15(1):15634. doi: 10.1038/s41598-025-98892-2.
3
Instantaneous in vivo distal edge verification in intensity-modulated proton therapy by means of PET imaging.
Med Phys. 2025 Jul;52(7):e17850. doi: 10.1002/mp.17850. Epub 2025 May 2.
4
Less may be more in PET (with AI).
Eur Radiol. 2025 Mar 24. doi: 10.1007/s00330-025-11483-7.
5
Quantitative Accuracy Assessment of the NeuroEXPLORER for Diverse Imaging Applications: Moving Beyond Standard Evaluations.
J Nucl Med. 2025 Jan 3;66(1):150-157. doi: 10.2967/jnumed.124.268309.
6
Enhanced Timing Performance of Dual-Ended PET Detectors for Brain Imaging Using Dual-Finishing Crystal Approach.
Sensors (Basel). 2024 Oct 10;24(20):6520. doi: 10.3390/s24206520.
7
Mesoscale Brain Mapping: Bridging Scales and Modalities in Neuroimaging - A Symposium Review.
Neuroinformatics. 2024 Oct;22(4):679-706. doi: 10.1007/s12021-024-09686-2. Epub 2024 Sep 23.
本文引用的文献
1
The PETcoil project: PET performance evaluation of two detector modules for a second generation RF-penetrable TOF-PET brain dedicated insert for simultaneous PET/MRI.
Phys Med Biol. 2023 Apr 5;68(8). doi: 10.1088/1361-6560/acc3f2.
2
Study of compatibility between a 3T MR system and detector modules for a second-generation RF-penetrable TOF-PET insert for simultaneous PET/MRI.
Med Phys. 2023 Jun;50(6):3389-3400. doi: 10.1002/mp.16354. Epub 2023 Apr 7.
3
A cycle-consistent adversarial network for brain PET partial volume correction without prior anatomical information.
Eur J Nucl Med Mol Imaging. 2023 Jun;50(7):1881-1896. doi: 10.1007/s00259-023-06152-0. Epub 2023 Feb 20.
4
A conformal TOF-DOI Prism-PET prototype scanner for high-resolution quantitative neuroimaging.
Med Phys. 2023 Jan 18. doi: 10.1002/mp.16223.
5
Performance evaluation of VRAIN: a brain-dedicated PET with a hemispherical detector arrangement.
Phys Med Biol. 2022 Nov 16;67(22). doi: 10.1088/1361-6560/ac9e87.
6
PET scatter estimation using deep learning U-Net architecture.
Phys Med Biol. 2023 Mar 10;68(6). doi: 10.1088/1361-6560/ac9a97.
7
Small nuclei identification with a hemispherical brain PET.
EJNMMI Phys. 2022 Oct 8;9(1):69. doi: 10.1186/s40658-022-00498-4.
8
Performance evaluation of dedicated brain PET scanner with motion correction system.
Ann Nucl Med. 2022 Aug;36(8):746-755. doi: 10.1007/s12149-022-01757-1. Epub 2022 Jun 13.
9
Application of artificial intelligence in brain molecular imaging.
Ann Nucl Med. 2022 Feb;36(2):103-110. doi: 10.1007/s12149-021-01697-2. Epub 2022 Jan 14.
10
A Novel J-Shape Antenna Array for Simultaneous MR-PET or MR-SPECT Imaging.
IEEE Trans Med Imaging. 2022 May;41(5):1104-1113. doi: 10.1109/TMI.2021.3132576. Epub 2022 May 2.
Zotero 插件