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因手术时间延长导致的髋部骨折后并发症发生率取决于患者个体的骨折类型及其治疗方式。

Rate of Complications after Hip Fractures Caused by Prolonged Time-to-Surgery Depends on the Patient's Individual Type of Fracture and Its Treatment.

作者信息

Daginnus Alina, Schmitt Jan, Graw Jan Adriaan, Soost Christian, Burchard Rene

机构信息

Faculty of Medicine, University of Marburg, 35037 Marburg, Germany.

Department of Orthopaedics and Traumatology, University Hospital of Giessen and Marburg, 35043 Marburg, Germany.

出版信息

J Pers Med. 2023 Oct 8;13(10):1470. doi: 10.3390/jpm13101470.

Abstract

INTRODUCTION

Hip fractures are common injuries in the elderly and are usually treated with timely surgery. While severe postoperative complications are reported for up to 10% of patients, many studies identified predictive factors for the occurrence of complications postoperatively. A controversially discussed factor is "time-to-surgery". The aim of the study was to examine if time-to-surgery was associated with the occurrence of complications and if the complication rate differed between the patient individual fracture types of intracapsular on the one hand and extracapsular hip fractures on the other hand. We hypothesized that time-to-surgery had less impact on complications in intracapsular hip fractures compared to extracapsular ones, and therefore, guidelines should pay attention to the patient individual case scenario.

MATERIALS AND METHODS

All patients who were admitted to the Department of Trauma and Orthopaedic Surgery of an academic teaching hospital for hip fracture surgery ( = 650) over a five-year period were included in the study. After the application of the exclusion criteria, such as periprosthetic or pathologic fractures, cases needed immediate surgical treatment, and after outlier adjustment, 629 cases remained in the study. Hip fractures were classified into intracapsular fractures (treated by hip arthroplasty) and extracapsular fractures (treated by intramedullary nailing osteosynthesis). The occurrence of severe complications in patients treated within 24 h was compared with patients treated later than 24 h after injury. For statistical evaluation, a multivariate logistic regression analysis was performed to investigate the impact of time-to-surgery interval on the occurrence of complications.

RESULTS

Patients with an extracapsular fracture, which was treated with intramedullary nailing (44.5%), rarely suffered a serious complication when surgery was performed within 24 h after injury. However, when the interval of the time-to-surgery was longer than 24 h, the complication rate increased significantly (8.63% vs. 25.0%, = 0.002). In contrast to this finding in patients with intracapsular fractures (55.5%), which were treated with cemented arthroplasty, complication rates did not depend on the 24 h interval (26.17% vs. 20.83%, = 0.567).

CONCLUSIONS

The occurrence of complications after surgical treatment of hip fractures is associated with the time interval between injury and surgery. A 24 h time interval between injury and surgical procedure seems to play a major role only in extracapsular fractures treated with osteosynthesis but not in intracapsular fractures treated with arthroplasty. Therefore, guidelines should take notice of the patient individual case scenario and, in particular, the individual hip fracture type.

摘要

引言

髋部骨折是老年人常见的损伤,通常采用及时手术治疗。虽然据报道高达10%的患者会出现严重的术后并发症,但许多研究确定了术后并发症发生的预测因素。一个备受争议的因素是“手术时间”。本研究的目的是探讨手术时间是否与并发症的发生有关,以及囊内骨折和囊外髋部骨折这两种不同类型的骨折患者之间的并发症发生率是否存在差异。我们假设,与囊外髋部骨折相比,手术时间对囊内髋部骨折并发症的影响较小,因此,指南应关注患者的个体情况。

材料与方法

本研究纳入了一家学术教学医院创伤与骨外科收治的所有因髋部骨折手术入院的患者(n = 650),研究时间跨度为五年。在应用排除标准后,如假体周围骨折或病理性骨折、需要立即手术治疗的病例,以及进行异常值调整后,共有629例患者纳入研究。髋部骨折分为囊内骨折(采用髋关节置换术治疗)和囊外骨折(采用髓内钉固定术治疗)。将伤后24小时内接受治疗的患者与伤后24小时后接受治疗的患者的严重并发症发生率进行比较。为进行统计学评估,采用多因素逻辑回归分析来研究手术时间间隔对并发症发生的影响。

结果

采用髓内钉固定治疗的囊外骨折患者(44.5%),若在伤后24小时内进行手术,很少发生严重并发症。然而,当手术时间间隔超过24小时时,并发症发生率显著增加(8.63%对25.0%,P = 0.002)。与采用骨水泥型关节置换术治疗的囊内骨折患者(55.5%)的这一结果相反,并发症发生率并不取决于24小时的时间间隔(26.17%对20.83%,P = 0.567)。

结论

髋部骨折手术治疗后并发症的发生与受伤至手术的时间间隔有关。受伤至手术的24小时时间间隔似乎仅在采用固定术治疗的囊外骨折中起主要作用,而在采用关节置换术治疗的囊内骨折中并非如此。因此,指南应关注患者的个体情况,尤其是个体髋部骨折类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/afe8/10608594/dca7f1d183a2/jpm-13-01470-g001.jpg

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